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0:00 -Introduction
0:39 - The Game-changing Study
1:24 - Why everything changed...
3:11 - Serious Side Effects...
6:00 - Take-Aways

References
[Study 413] SPRINT Research Group, Wright JT Jr, Williamson JD, et al. A Randomized Trial of Intensive versus Standard Blood-Pressure Control [published correction appears in N Engl J Med. 2017 Dec 21;377(25):2506. doi: 10.1056/NEJMx170008.]. N Engl J Med. 2015;373(22):2103-2116. doi:10.1056/NEJMoa1511939

Funding/Conflicts: Public Funding [National Institutes of Health (NIH); Clinical and Translational Science Awards; Department of Veterans Affairs] // Potential Conflicts of Interest [Drugs were donated by Takeda and Arbor Pharmaceutical]

[Study 414] SPRINT Research Group, Lewis CE, Fine LJ, et al. Final Report of a Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2021;384(20):1921-1930. doi:10.1056/NEJMoa1901281

Funding/Conflicts: Public Funding [National Institutes of Health (NIH); Clinical and Translational Science Awards; Department of Veterans Affairs] // Potential Conflicts of Interest [Drugs were donated by Takeda and Arbor Pharmaceutical]

********CRITIQUES, RULES, AND NOTES********

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