
Berberine: A Cure for Metabolic Disorder?
Physionic
6 nov 2024
Mindsip insights from this episode:
Critique flawed Berberine study for accurate results
A better Berberine study was still flawed, as researchers forgot to include the main result for triglycerides and failed to specify the units of measurement.
Critique unreliable meta-analysis on Berberine research
A popular meta-analysis on Berberine is completely untrustworthy due to egregious errors, like standard deviations reported as being "over 9,000.".
Seek pre-registered studies for unbiased meta-analyses
Higher quality meta-analyses are often pre-registered in a database like Prospero, which reduces bias by having researchers declare their questions beforehand.
Utilize berberine to lower long-term blood sugar levels
A more rigorous analysis confirms that Berberine supplementation effectively reduces HbA1c, a key marker of long-term blood sugar control.
Improve insulin resistance with berberine consumption
Berberine consumption improves the HOMA-IR index, indicating it helps reduce insulin resistance, a major risk factor for metabolic diseases.
Utilize berberine to improve blood sugar and insulin levels
Despite flawed analyses, the trend in individual studies suggests Berberine probably improves blood sugar, insulin, and triglycerides for those with or at risk of type 2 diabetes.
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