JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 HEALTH AUTONOMY [COURSE]Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomyJOIN THE COMMUNITYJoin my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2EMAIL LIST1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6HIRE ME FOR CONSULTING: Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction0:54 - Weight Fluctuations and Cardiovascular Disease7:46 - Main Points / Key TakeawaysReferences[Study 543] Bangalore S, Fayyad R, Laskey R, DeMicco DA, Messerli FH, Waters DD. Body-weight fluctuations and outcomes in coronary disease. N Engl J Med. 2017;376(14):1332-1340. doi:10.1056/NEJMoa1606148 Funding/Conflicts: Public funding: No governmental or other public funding sources are reported for this study; no public-funder–related conflicts of interest are described in the article. Non-profit funding: No non-profit or charitable funding sources are reported; no non-profit–linked conflicts of interest are described in the article. Industry funding: The study was supported by Pfizer, and three authors (R.F., R.L., and D.A.D.) are affiliated with Pfizer, indicating industry sponsorship and author employment–related financial ties to the funder.[Study 544] Scolaro B, Krautter F, Brown EJ, et al. Caloric restriction promotes resolution of atherosclerosis in obese mice, while weight regain accelerates its progression. J Clin Invest. 2025;doi:10.1172/JCI172198Funding/Conflicts: Public funding: No governmental or other public funding sources are reported for this study, and no public-funder–related conflicts of interest are described; Non-profit funding: The article does not list any non-profit or charitable funding sources, and no non-profit–linked conflicts of interest are reported; Industry funding: No industry or commercial funding sources are specified, and the authors explicitly state that they have no conflicts of interest. CRITIQUES, RULES, AND NOTESBe aware of the following rules before posting comments:- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES:If your comment is rude, you will be banned.If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!). Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes. #heartdisease #cardiovascularhealth