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0:00 - Introduction
1:33 - A Shift in Metabolism...
4:15 - Why do our arteries prefer this metabolic state?
9:54 - What can we do to fix these arterial problems?
13:51 - Main Points
Reference
[Study 490] Kalucka J, Bierhansl L, Vasconcelos Conchinha N, et al. Quiescent endothelial cells upregulate fatty acid β‑oxidation for vasculoprotection via redox homeostasis. Cell Metab. 2018;28(6):881‑894. doi:10.1016/j.cmet.2018.07.016
Funding/Conflicts: Mixed Funding [Public: Research Foundation Flanders (FWO), the Federal Government of Belgium (IUAP7/03), the Flemish Government through Methusalem structural funding, the Swiss National Science Foundation, the British Heart Foundation, the National Natural Science Foundation of China, and several European Union programs including the Marie Curie CIG and ERC Advanced Research Grant (EU-ERC743074). Additional public support came from institutions such as the State Key Laboratory of Ophthalmology (China) and the VIB Tech-Watch Program in Belgium.; Non-Profit: Leopoldina Postdoctoral Scholarship (Germany), the Fritz Thyssen Stiftung, and the Foundation Against Cancer (Belgium). // Potential direct Conflicts of Interest [Peter Carmeliet (P.C.) is named as an inventor on patent applications related to the findings in this paper; All other authors declare no competing interests.]
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