Dr. John Lieurance Reveals The Crazy Story of His Leg Amputation, Dives Into The Latest Methylene Blue Protocols & Tells You Why You Should Be Breathing Carbon Dioxide (& More!)

Ben Greenfield

May 1, 2025

Episode description

In this episode with repeat guest Dr. John Lieurance, you’ll get an inside look at some of the most cutting-edge—and controversial—topics in modern healing. From the truth about methylene blue (is it a miracle molecule or misunderstood toxin?) to the deeper story behind light therapy and mitochondrial health, Dr. Lieurance pulls back the curtain on what the mainstream gets wrong. You’ll also hear about his powerful recovery journey after a life-altering injury and below-the-knee amputation, and how it reshaped his approach to healing, resilience, and purpose. Plus, discover surprising insights on prostate health, the mysterious origins of Lyme disease, and the latest tools shaking up regenerative medicine. This episode is packed with takeaways that could radically shift how you think about your body, your health, and your potential to heal.

Full show notes: https://bengreenfieldlife.com/blueman

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Episode description

Full show notes: https://bengreenfieldlife.com/blueman

Episode Sponsors:

SuperTeeth: One of the first oral care brands that creates products that safely remineralize teeth without the need for fluoride. Visit GetSuperTeeth.com and use code BENGREENFIELD for 15% off.

Mindsip insights from this episode:

Recognize blue brain staining as effective mitochondrial targeting

Seeing a brain stained blue from methylene blue is not a sign of toxicity, but rather evidence that it is successfully reaching the mitochondria-rich brain tissue as intended.

#methylene-blue

#mitochondria

Cycle methylene blue use to maintain mitochondrial function

To prevent potential buildup and a slowing of the mitochondria, it is a good idea to take a couple of days off from methylene blue every 10 to 14 days.

#methylene-blue

#mitochondria

Investigate man-made origins of Lyme disease theory

A controversial theory suggests that modern Lyme disease is not a natural spirochete but a more virulent, man-made biological weapon developed on Plum Island after WWII.

#bacteria

#Lyme

Treat hidden prostate infections with Prostabluezone protocol

Many men may have hidden prostate infections, not just age-related growth, which can be treated with a 'Prostabluezone' protocol involving direct injections of antibiotics, methylene blue, and ozone.

#prostate

#protocol

Prevent partner infections by addressing prostate health

Infections like fungus or bacteria in a man's prostate gland can be passed to a female partner during intercourse, potentially causing her to experience recurrent UTIs or yeast infections.

#bacteria

#prostate

Biohack recovery with stem cells and peptides in hospital setting

After a severe injury, Dr. Lieurance secretly used smuggled-in stem cells, peptides, and methylene blue to reverse his kidney failure and aid recovery in the hospital.

#biohacking

#stem-cell

Inhale carbon dioxide to enhance recovery and calm anxiety

Inhaling 3-7% carbon dioxide for a few minutes can induce a calming, anxiolytic effect and trigger a large release of nitric oxide, aiding in recovery.