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0:00 - Introduction
1:20 - Nature's Ozempic?
4:21 - Is there any evidence?
10:25 - What are "true" natural Ozempics?
12:49 - Main Points

References
[A] Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Diabetes. 2008;57(5):1414-1418. doi:10.2337/db07-1552

[B] Nauck MA, Quast DR, Wefers J, Meier JJ. GLP-1 receptor agonists in the treatment of type 2 diabetes - state-of-the-art. Mol Metab. 2021;46:101102. doi:10.1016/j.molmet.2020.101102

[C] Xiong P, Niu L, Talaei S, et al. The effect of berberine supplementation on obesity indices: A dose- response meta-analysis and systematic review of randomized controlled trials. Complement Ther Clin Pract. 2020;39:101113. doi:10.1016/j.ctcp.2020.101113

[D] Wu XK, Wang YY, Liu JP, et al. Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome. Fertil Steril. 2016;106(3):757-765.e1. doi:10.1016/j.fertnstert.2016.05.022

[E] An Y, Sun Z, Zhang Y, Liu B, Guan Y, Lu M. The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment. Clin Endocrinol (Oxf). 2014;80(3):425-431. doi:10.1111/cen.12294

[F] Hjørne AP, Modvig IM, Holst JJ. The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion. Metabolites. 2022;12(5):420. Published 2022 May 7. doi:10.3390/metabo12050420

[G] Wu S, Jia W, He H, et al. A New Dietary Fiber Can Enhance Satiety and Reduce Postprandial Blood Glucose in Healthy Adults: A Randomized Cross-Over Trial. Nutrients. 2023;15(21):4569. Published 2023 Oct 27. doi:10.3390/nu15214569

[H] Bodinham CL, Al-Mana NM, Smith L, Robertson MD. Endogenous plasma glucagon-like peptide-1 following acute dietary fibre consumption. Br J Nutr. 2013;110(8):1429-1433. doi:10.1017/S0007114513000731

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