AMA #67: Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk
Peter Attia
Jan 20, 2025
Mindsip insights from this episode:
Focus on particle size to assess plastic risk
The primary concern with plastics is not the total mass consumed but the size of the particles, as only very small nanoplastics can be absorbed by the body.
Debunk myth of consuming a credit card's worth of plastic weekly
The popular claim that humans consume a credit card's worth of plastic (5 grams) per week has been largely debunked, with more realistic estimates being 10 to 300 micrograms.
Eliminate 99% of ingested microplastics through stool
Approximately 99% of ingested microplastics are eliminated through stool, as they have a very difficult time crossing the gastrointestinal barrier.
Recognize inhaling plastic as direct bloodstream injection
Inhaling airborne particles smaller than 2.5 micrometers can allow them to cross into the bloodstream directly from the lungs, similar to being injected.
Question safety of 'BPA-free' plastics due to substitutes
Plastics labeled 'BPA-free' are often made with substitutes like BPS and BPF, and it is not clear if these are any better for your health.
Inspect shampoos for phthalate exposure
Your greatest exposure to phthalates, chemicals that make plastics flexible, likely comes from personal care products like shampoos and lotions where their use is largely unrestricted.
Navigate complexities of microplastics for informed discussions
The topic of microplastics is so complex and filled with incomplete information that it was the most difficult and frustrating subject the host has ever prepared for an episode.
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