How To Microdose GLP-1 (& How To Make Eating Less EASY Even After You Stop Your Peptides) With Geoff Cook of NOOM

Ben Greenfield

Jan 1, 2026

Episode description

Full Show Notes: https://bengreenfieldlife.com/noompodcast/

In this episode, Geoff Cook, CEO of Noom, talks about the science and practicalities of GLP-1 microdosing for weight loss and longevity. He breaks down what microdosing means, how Noom combines low-dose GLP-1 with behavior change programs to promote sustainable results, and the broader health benefits beyond just weight loss—such as improved metabolic markers and reduced inflammation. The conversation also covers safety, affordability, and Noom's new at-home blood testing for tracking progress.

Geoff Cook is the CEO of Noom. He is also a serial entrepreneur and long-time public company CEO. He co-founded The Meet Group, a NASDAQ-listed social dating and live-streaming company connecting millions of active users globally. Geoff served as The Meet Group’s CEO from 2013 to 2023, leading it through its sale for $500 million in 2020.

Noom Health partners with top health plans and employers to offer a suite of solutions, including Noom Med, Noom Med with SmartRx, Noom Weight, Noom Weight with GLP-1Rx, Noom Diabetes, and Noom Diabetes Prevention Program, to millions. Noom has received multiple National Institute of Health grants and was the first mobile app recognized by the CDC as a certified diabetes prevention program.

You can visit Noom and use the code BGNOOM to save 10% off.

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Episode description

Full Show Notes: https://bengreenfieldlife.com/noompodcast/

You can visit Noom and use the code BGNOOM to save 10% off.

Episode Sponsors:

Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at

Mindsip insights from this episode:

Reduce food noise to enhance cognitive bandwidth

'Food noise' may be the brain's default mode network constantly simulating future meals, and reducing it frees up significant cognitive bandwidth.

#appetite

#cognition

Utilize Tasso device for painless at-home blood testing

The Tasso device is a virtually painless, at-home blood collection tool that sticks to your arm to fill a vial for lab testing.

#blood-test

#device

Increase food enjoyment while reducing cravings with GLP-1s

An fMRI study found that GLP-1s increased the 'liking' for a food but decreased the 'wanting' or craving for it.

#craving

#GLP1

Maintain weight after discontinuing GLP-1s for lasting success

A real-world study by EPIC found that about 50% of people kept their weight off a year after discontinuing GLP-1s, which is more successful than pharmaceutical trials suggest.

#GLP1

#weight-loss

Increase GLP-1 medication adherence for better outcomes

A recent study by Prime Therapeutics showed that only 8 out of 100 people are still on GLP-1 medication after three years.

#GLP1

Reduce inflammation with GLP-1s before weight loss

GLP-1s can cause a marked reduction in inflammation, measured by hs-CRP, within the first few weeks, often before any significant weight loss occurs.

#GLP1

#inflammation

Define GLP-1 microdose as 2% to 25% of standard dose

A microdose of a GLP-1 agonist is generally defined as being 2% to 25% of the standard high maintenance dose.

#GLP1

#microdosing

Ensure compounding pharmacy sources meet FDA standards for safety

Regulated compounding pharmacies (503A) must source their active ingredients from an FDA 'greenlisted' provider and have a certificate of authenticity for purity.