
Medications I take for a healthier, longer life
Brad Stanfield
May 15, 2024
Mindsip insights from this episode:
Investigate empagliflozin's potential to slow kidney decline
Empagliflozin, a diabetes drug that increased lifespan in mice, is being studied to see if it can slow down age-related kidney decline in non-diabetic people.
Combine Ezetimibe with statins for effective cholesterol management
Instead of increasing a statin's dosage to lower cholesterol, adding Ezetimibe can be more effective and result in fewer side effects.
Utilize finasteride to enhance prostate cancer detection
Finasteride may not cause more aggressive prostate cancer but rather improves its detection by shrinking the prostate, a phenomenon known as detection bias.
Implement low-dose finasteride strategy for early intervention
The speaker takes a 1mg dose of finasteride, which is lower than the 5mg dose used in clinical trials, hoping it's sufficient when started at a younger age.
Manage LDL cholesterol to prevent blood vessel blockages
The PESA study showed that even when all other risk factors like inflammation are optimal, high LDL cholesterol is still directly correlated with blockages in blood vessels.
Aim for aggressive LDL cholesterol target of 20 to 40 mg/dL
Research suggests the optimal LDL cholesterol level may be the level present at birth, which is an aggressive target of 20 to 40 milligrams per deciliter.
Utilize low-dose statins for effective treatment with fewer side effects
Low-dose statins can offer 70-80% of the benefits of high-dose statins but with a much lower risk of side effects.
Choose rosuvastatin for reduced brain and muscle impact
Rosuvastatin is a good choice because it is hydrophilic, meaning it doesn't readily cross the blood-brain barrier or accumulate in muscles.
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