The Little-Known Sleep-Enhancing Molecule Most People Don't Understand: Truth About GABA & Sleep Hacking With Dr. Scott Sherr.

Ben Greenfield

Feb 22, 2024

Episode description

Do you find yourself battling with anxiety that grips your chest or insomnia that keeps you tossing and turning through the night? If so, this episode equips you with actionable strategies that lead toward a calmer, more revitalized you.

Dive into the depths of neurotransmitter science with Dr. Scott Sherr as he unravels the mysteries of GABA modulation and helps you discover how rebalancing GABA levels can calm the storms of anxiety, pave the way for restful sleep, and unlock a path to overall well-being. 

Dr. Scott Sherr is a Board Certified Internal Medicine Physician certified to practice Health Optimization Medicine (HOMe) and a specialist in hyperbaric oxygen therapy (HBOT). He is the founder of HOMe-SF, the first HOMe clinic in the United States, and the Chief Operating Officer of Health Optimization Medicine and Practice (HOMe/HOPe)–USA, a nonprofit education company training doctors and healthcare practitioners in detecting and correcting the root causes of health, not just disease.

Additionally, Dr. Scott is also the COO of Smarter Not Harder (SNH), the for-profit arm of HOMe/HOPe. SNH is the company behind Troscriptions, a line of precision-dosed buccal troches that address the bottlenecks along the path to optimal health. They have five products on the market, now including Blue Cannatine, Just Blue, Tro+ Blue, Tro Calm, and Tro Zzz.

Dr. Scott is also the co-founder of OneBase Health, an innovative HBOT ecosystem leveraging synergistic technologies to accelerate results. His clinical practice includes HOMe as its foundation, along with an integrative approach to hyperbaric oxygen therapy. This approach encompasses cutting-edge and dynamic HBOT protocols, comprehensive laboratory testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new and ancient), and more.

Prepare to embark on a fascinating journey into the intricate world of GABA. Join me and Dr. Scott as we unravel the profound impact of this neurotransmitter on anxiety, sleep, and your overall well-being. This enlightening discussion is brimming with practical insights to help you optimize your GABA levels and elevate your quality of life.

For the full show notes, visit: https://bengreenfieldlife.com/gabapodcast

Episode Sponsors:

JoyMode: Go to usejoymode.com/GREENFIELD or enter GREENFIELD at checkout for 20% off your first order.

BiOptimizers Magnesium Breakthrough: Go to

Episode description

Do you find yourself battling with anxiety that grips your chest or insomnia that keeps you tossing and turning through the night? If so, this episode equips you with actionable strategies that lead toward a calmer, more revitalized you.

Dive into the depths of neurotransmitter science with Dr. Scott Sherr as he unravels the mysteries of GABA modulation and helps you discover how rebalancing GABA levels can calm the storms of anxiety, pave the way for restful sleep, and unlock a path to overall well-being. 

Dr. Scott Sherr is a Board Certified Internal Medicine Physician certified to practice Health Optimization Medicine (HOMe) and a specialist in hyperbaric oxygen therapy (HBOT). He is the founder of HOMe-SF, the first HOMe clinic in the United States, and the Chief Operating Officer of Health Optimization Medicine and Practice (HOMe/HOPe)–USA, a nonprofit education company training doctors and healthcare practitioners in detecting and correcting the root causes of health, not just disease.

Additionally, Dr. Scott is also the COO of Smarter Not Harder (SNH), the for-profit arm of HOMe/HOPe. SNH is the company behind Troscriptions, a line of precision-dosed buccal troches that address the bottlenecks along the path to optimal health. They have five products on the market, now including Blue Cannatine, Just Blue, Tro+ Blue, Tro Calm, and Tro Zzz.

Dr. Scott is also the co-founder of OneBase Health, an innovative HBOT ecosystem leveraging synergistic technologies to accelerate results. His clinical practice includes HOMe as its foundation, along with an integrative approach to hyperbaric oxygen therapy. This approach encompasses cutting-edge and dynamic HBOT protocols, comprehensive laboratory testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new and ancient), and more.

Prepare to embark on a fascinating journey into the intricate world of GABA. Join me and Dr. Scott as we unravel the profound impact of this neurotransmitter on anxiety, sleep, and your overall well-being. This enlightening discussion is brimming with practical insights to help you optimize your GABA levels and elevate your quality of life.

For the full show notes, visit: https://bengreenfieldlife.com/gabapodcast

Episode Sponsors:

JoyMode: Go to usejoymode.com/GREENFIELD or enter GREENFIELD at checkout for 20% off your first order.

BiOptimizers Magnesium Breakthrough: Go to

Mindsip insights from this episode:

Utilize Troi's natural ingredients for deep sleep enhancement

The sleep product Troi combines Agarin, Hanakayl, CBD, CBN, adenosine to counteract caffeine, and cordycepin for deep sleep.

Utilize cordycepin to enhance deep sleep quality

Contrary to its reputation as a stimulant, the mushroom compound cordycepin actually increases slow-wave (deep) sleep.

Recognize THC's potential to induce anxiety by inhibiting GABA

THC inhibits the release of the calming neurotransmitter GABA, which can paradoxically cause anxiety in some users.

Utilize Agarin from Amanita Muscaria for restful sleep

A compound called Agarin, from the Amanita Muscaria mushroom, is a long-acting GABA supporter for sleep that doesn't cause a psychedelic experience.

Reframe your day to prioritize sleep

To better prioritize sleep, adopt the mindset that your day starts when you go to bed, not when you wake up.

Investigate genetic links between alcoholism and GABA production

A family history of alcoholism may indicate a genetic predisposition to vitamin and mineral deficiencies that impair GABA production, rather than a direct issue with GABA receptors.

Place dissolvable troches between upper cheek and gum for optimal absorption

For best absorption, dissolvable troches should be placed between the upper cheek and gum, which has eight layers of mucosa, not in the lower lip.

Utilize Nicotinyl GABA for calm focus without drowsiness

A special form of GABA attached to a vitamin B3 molecule, called Nicotinyl GABA, can cross the blood-brain barrier to provide calm focus without drowsiness.

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