How To Microdose GLP-1 (& How To Make Eating Less EASY Even After You Stop Your Peptides) With Geoff Cook of NOOM
Ben Greenfield
1 ene 2026
Mindsip insights from this episode:
Reduce food noise to enhance cognitive bandwidth
'Food noise' may be the brain's default mode network constantly simulating future meals, and reducing it frees up significant cognitive bandwidth.
Utilize Tasso device for painless at-home blood testing
The Tasso device is a virtually painless, at-home blood collection tool that sticks to your arm to fill a vial for lab testing.
Increase food enjoyment while reducing cravings with GLP-1s
An fMRI study found that GLP-1s increased the 'liking' for a food but decreased the 'wanting' or craving for it.
Maintain weight after discontinuing GLP-1s for lasting success
A real-world study by EPIC found that about 50% of people kept their weight off a year after discontinuing GLP-1s, which is more successful than pharmaceutical trials suggest.
Increase GLP-1 medication adherence for better outcomes
A recent study by Prime Therapeutics showed that only 8 out of 100 people are still on GLP-1 medication after three years.
Reduce inflammation with GLP-1s before weight loss
GLP-1s can cause a marked reduction in inflammation, measured by hs-CRP, within the first few weeks, often before any significant weight loss occurs.
Define GLP-1 microdose as 2% to 25% of standard dose
A microdose of a GLP-1 agonist is generally defined as being 2% to 25% of the standard high maintenance dose.
Ensure compounding pharmacy sources meet FDA standards for safety
Regulated compounding pharmacies (503A) must source their active ingredients from an FDA 'greenlisted' provider and have a certificate of authenticity for purity.
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