
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern
Andrew Huberman
May 7, 2026
Episode description
In this Huberman Lab Essentials episode, my guest is Dr. Casey Halpern, MD, a professor of neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. We discuss how deep brain stimulation and other neuromodulation approaches are being used to treat Parkinson's disease, obsessive-compulsive disorder (OCD), binge eating disorder and depression-related symptoms. We also explore the brain circuits that drive compulsions, cravings and impulsivity, as well as emerging non-invasive tools for predicting and treating harmful behaviors.
Show notes: https://go.hubermanlab.com/QTgU0Jx
Watch more Huberman Lab Essentials: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S&si=a1_sA7rUT-fE0OM5
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Timestamps
00:00:00 Casey Halpern
00:00:20 Neurosurgery, Deep Brain Stimulation
00:04:19 Obsessive-Compulsive Disorder (OCD) & Treatments
00:10:11 OCD Brain Areas, Addiction
00:12:34 Nucleus Accumbens, Risk & Rewards; Binge Eating Disorder
00:16:50 Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation
00:24:33 Awareness of Cravings, Severe Binge Eating Disorder
00:28:38 Artificial Intelligence/Machine Learning & Predicting Impulsive Behavior
00:32:44 Acknowledgements
#hubermanlab
Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer
Mindsip insights from this episode:
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