How Cannabis Impacts Health & the Potential Risks | Dr. Matthew Hill
Andrew Huberman
Jul 8, 2024
Mindsip insights from this episode:
Exercise to release stored THC and impact drug tests
Because THC is stored in fat, exercising or losing weight can release it back into the bloodstream, potentially causing a positive drug test after previously testing negative.
Recognize cannabis as potential trigger for schizophrenia onset
The expert view is that cannabis doesn't cause schizophrenia, but for those already predisposed, it can act as 'fuel on a fire,' accelerating its onset and worsening the prognosis.
Exercise caution with high-potency cannabis concentrates
High-potency cannabis concentrates are incredibly challenging to self-titrate and can lead to blood THC levels two to three times higher than with cannabis flower.
Self-regulate THC intake for consistent effects
Whether using low or high-potency cannabis flower, users tend to self-regulate their intake to achieve similar blood levels of THC, around 100 nanograms per milliliter.
Enhance anandamide levels to reduce stress without intoxication
Drugs that block the breakdown of the body's own anandamide can increase its levels to reduce stress and fear without causing the psychoactive 'high' associated with THC.
Shift emotional perception of pain with cannabis
For chronic pain, cannabis is effective not by being a powerful painkiller, but by changing the emotional perception of pain, pushing it into the 'background noise.'.
Recognize placebo effect in most commercial CBD products
The doses of CBD in most commercial products are hundreds of times lower than the doses shown to be clinically effective, suggesting most reported benefits are a placebo effect.
Recognize expectancy bias in Indica vs Sativa effects
The reported differences in effects between Indica and Sativa strains are likely due to expectancy bias, as there is no consistent chemical profile that distinguishes them.
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