How Jeff Bland Reversed His Biological Age at 79 (Part 1)
Mark Hyman
May 28, 2025
Episode description
Dr. Jeff Bland has been called the father of Functional Medicine—and for good reason. His groundbreaking work helped shift our understanding of chronic disease and inspired a generation of doctors to look beyond symptoms and toward root causes. On this episode of The Dr. Hyman Show, I sit down with Jeff to talk about what he’s learned from more than 50 years of studying the science of health, aging, and disease prevention.
We explore:
• Why your biology is not predetermined by your genes—and how to unlock your full potential
• What Jeff’s own health journey reveals about inflammation, biomarkers, and aging well
• How what you eat can shape everything from inflammation to longevity
• Long-term disease risk is shaped by what surrounds you—and how your body responds
Tune in for an insightful conversation with one of my greatest mentors—and discover how science, curiosity, and personal agency can help you live a longer, healthier life.
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Mindsip insights from this episode:
Incorporate colorful foods to prevent long latency deficiency diseases
A long-term lack of phytochemicals, the compounds that give plants their color, can lead to 'long latency deficiency diseases' like cancer and dementia.
Utilize Seed DS-01 Daily Synbiotic for clear, hydrated skin
The Seed DS-01 Daily Synbiotic contains specific probiotic strains that are clinically validated to support clear and hydrated skin through the gut-skin axis.
Practice immuno-rejuvenation for a healthier immune system
Instead of just 'boosting' your immune system, you can practice 'immuno-rejuvenation' because your immune cells completely turn over every 120 days.
Understand three systems connecting body to the world
Your body has only three systems that constantly communicate with the outside world: the nervous system, the mucosal surfaces like the gut, and the immune system.
Prioritize mitochondrial health to support energy-hungry immune system
When you are ill, your immune system can consume up to 50% of your body's total metabolic energy, highlighting the importance of mitochondrial health.
Train innate immune system with polyphenols for resilience
The innate immune system, your body's first line of defense, can be trained to be more resilient by consuming polyphenols from plants.
Utilize Himalayan Tartary Buckwheat to enhance immune regulation
Himalayan Tartary Buckwheat is an ancient, gluten-free plant containing high levels of phytochemicals that can help regulate and train your immune system.
Detect Alzheimer's risk early with P-Tau217 blood test
A biomarker called P-Tau217 can be detected in the blood to identify Alzheimer's risk decades before any symptoms appear, allowing for early intervention.
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