How To Maximize Hormones And Maintain Fertility (+ Are Old-School Approaches To Testosterone DANGEROUS or INEFFECTIVE?) With Dr. Cameron Sepah of Maximus Tribe.

Ben Greenfield

Oct 26, 2024

Episode description

In this episode with Dr. Cameron Sepah, you'll get to dive into critical topics like the alarming drop in testosterone and sperm counts, the dangers of endocrine-disrupting chemicals, and why testosterone replacement therapy (TRT) could harm fertility. You'll explore the difference between primary and secondary hypogonadism, alternative therapies like Clomid or enclomiphene that boost natural testosterone production, and the challenges of maintaining fertility during TRT. You'll also hear about the risks of high estrogen levels, the impact of testosterone on libido, the importance of personalized dosing, and cutting-edge innovations like at-home devices that measure key hormones with clinical accuracy.

Dr. Cameron Sepah is the CEO of Maximus, an online medical clinic specializing in health and hormone optimization, backed by top venture capitalists including Founders Fund, 8VC, and angel investors such as Dave Asprey of Bulletproof, Ryan Holiday of the Daily Stoic, and the executives behind The Honest Company, Coinbase, Tinder, and Shopify.

Cameron is a serial health tech entrepreneur, as a founding team member of Omada Health, a billion-dollar startup that pioneered the field of digital therapeutics. He is a licensed clinical psychologist by training, specializing in behavioral medicine, and a clinical professor of psychiatry, where he trains doctors in evidence-based health care.

Tune in to get all the insights you need to make informed decisions about optimizing your testosterone, fertility, and overall health!

Full Show notes: https://bengreenfieldlife.com/maximuspodcast

SiPhox: Visit siphoxhealth.com/ben with code BEN to get 20% off your health kit!

Pendulum: Get 20% off your first month of any Pendulum probiotic with code GREENFIELD at

Episode description

Tune in to get all the insights you need to make informed decisions about optimizing your testosterone, fertility, and overall health!

Full Show notes: https://bengreenfieldlife.com/maximuspodcast

SiPhox: Visit siphoxhealth.com/ben with code BEN to get 20% off your health kit!

Pendulum: Get 20% off your first month of any Pendulum probiotic with code GREENFIELD at

Mindsip insights from this episode:

Reevaluate testosterone lab ranges for optimal health

Standard testosterone lab reference ranges are problematic because they aren't age-referenced and include data from a largely unhealthy population, making 'normal' a poor indicator of 'optimal'.

#blood-test

#testosterone

Address male fertility crisis to prevent zero sperm count by 2050

If the current trend continues, society could theoretically hit a sperm count of zero by 2050, highlighting a massive and growing male fertility problem.

#fertility

Avoid cheap at-home blood tests for accurate results

The common and cheap 'dried blood spot' tests are often inaccurate due to collection issues and temperature sensitivity, making them less reliable than whole-blood collection devices.

#blood-test

#testing

Stimulate testosterone production with Enclomiphene for fertility

Unlike injectable TRT which shuts down natural production, Enclomiphene stimulates your body to produce more testosterone, increasing testicular volume and fertility.

#Enclomiphene

#testosterone

Choose purified Enclomiphene over Clomid for better mood stability

Clomid contains an estrogen-like molecule called Zuclomiphene that causes moodiness, making purified Enclomiphene a superior option for men.

#Enclomiphene

Utilize modern oral testosterone to bypass liver toxicity

Modern oral testosterone is designed to be absorbed via the lymphatic system with fats, bypassing first-pass liver metabolism and avoiding the liver toxicity of older oral steroids.

#testosterone

Utilize oral testosterone to naturally regulate estrogen levels

Oral and topical testosterone preferentially metabolize into DHT, which acts as the body's natural aromatase inhibitor, often eliminating the need for AI drugs.

#estrogen

#testosterone

Combine enclomiphene with oral testosterone to maintain LH and FSH levels

Combining Enclomiphene with oral testosterone can mitigate the suppressive effects of the exogenous testosterone, maintaining normal LH and FSH levels.