Plasma exchange, a process of cleaning your blood by removing old plasma and its inflammatory components, may have the most significant impact on reversing biological age.

A groundbreaking study showed that a plant-rich, keto-leaning diet with exercise and supplements reversed biological age by an average of 3.23 years in just eight weeks.

The principle of phytohormesis suggests that small, non-lethal doses of plant toxins, like those in cruciferous vegetables, beneficially stress your body to activate healing and anti-inflammatory pathways.

Research from the Salk Institute found that time-restricted eating affects the expression of approximately 70% of genes, influencing hormones and activating anti-aging pathways like autophagy.

Taking 4,000 units of vitamin D3 daily, with no other changes, was shown in one study to reduce biological age by 1.85 years in just 16 weeks.

Fisetin, a phytochemical from strawberries, can be supplemented at 500-1000 milligrams to help kill inflammatory senescent "zombie cells" that accumulate with age.

Urolithin A, a postbiotic made from pomegranates by gut bacteria, can be supplemented with a product called Mitopure to improve mitochondrial health.

Specific peptides like BPC-157 and Thymosin Alpha-1 are emerging regenerative therapies that can be used to help with healing and immunity.