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Next Video (Curcumin on Arthritis): https://youtu.be/ztQphqkwLNU?si=d160q4QetKne3VGd

0:00 - Introduction
2:14 - The Poisoning... A Shakespearean Play?
4:05 - Four Solutions
6:51 - Main Points

References
[Study 513] Xiang W, Zhang T, Li B, et al. Senescent macrophages induce ferroptosis in skeletal muscle and accelerate osteoarthritis-related muscle atrophy. Nature Aging. 2025;5:1295-1316. doi:10.1038/s43587-025-00907-0.

Funding/Conflicts: Public Funding [National Natural Science Foundation of China (82394444, Lin Chen; 82372495, Z.N.; 82202770, W.X.); the Natural Science Foundation of Chongqing (CSTB2022NSCQ-MSX1267, Z.N.; CSTB2022NSCQ-MSX0863, W.X.); the State Key Laboratory of Trauma, Burn and Combined Injury (project SKL2021JY01; Z.N.); the Chongqing Municipal Healthcare Technology Promotion Project (2020jstg028; S.Z.); the Chongqing Acute and Critical Care Clinical Medical Research Center (3354181; S.Z.); and the “War Group” of the Army’s 14th Five-Year Construction Project: War Trauma Treatment Group (S.Z.)] // No direct Conflicts of Interest

[A] Nachvak SM, Alipour B, Mahdavi AM, et al. Effects of coenzyme Q10 supplementation on matrix metalloproteinases and DAS-28 in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(12):3367-3374. doi:10.1007/s10067-019-04723-x

[B] Abdollahzad H, Aghdashi MA, Asghari Jafarabadi M, Alipour B. Effects of Coenzyme Q10 Supplementation on Inflammatory Cytokines (TNF-α, IL-6) and Oxidative Stress in Rheumatoid Arthritis Patients: A Randomized Controlled Trial. Arch Med Res. 2015;46(7):527-533. doi:10.1016/j.arcmed.2015.08.006

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