For people who have never had a heart attack, taking a statin for five years offers at best a 1% benefit in preventing a non-fatal heart attack or non-disabling stroke.

For people over 60, a higher LDL cholesterol level is inversely associated with all-cause mortality, meaning you are statistically less likely to die.

Coronary artery disease is not a plumbing problem of clogged pipes but a chronic inflammatory and immune problem exacerbated by metabolic risk factors like insulin resistance.

In subgroup analyses of statin trials, patients with normal triglycerides and HDL cholesterol received no benefit at all from the drug, even if they had a prior heart attack.

For patients with a genetic high-cholesterol condition (FH), their risk of heart disease almost returns to normal if they have a normal waist circumference and low insulin.

In one study, the only independent factor for reversing coronary artery disease was practicing 40 minutes of Raja yoga meditation daily, which led to a spiritual transformation.

Drug companies use a 'pre-randomization run-in phase' to remove participants who experience side effects before the trial officially begins, thus fraudulently underreporting the drug's true side effect profile.

For a high-risk person who has already had a heart attack, taking a statin for five years results in a median increase in life expectancy of just over four days.

Data from the Framingham studies showed that unless your LDL cholesterol is extremely high (around 250-300 mg/dL), it is useless as a predictor for coronary artery disease.