The WATER Hack That Boosts Mitochondria by 11%!

Dave Asprey

10 oct 2025

Episode description

What if you could improve your mitochondria, oxygen efficiency, and recovery in just 20 minutes a day—by breathing energized water? This episode explores one of the most surprising breakthroughs in biohacking and how it can help you live longer, think clearer, and perform better.

Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR

Host Dave Asprey talks with Rowena Gates, co-founder of NanoVi, a therapeutic device backed by biophysics research that supports protein repair and mitochondrial communication. Her work reveals how structured water inside your cells drives neuroplasticity, cellular regeneration, and stress resilience—offering a new pathway to recovery, energy, and longevity.

You’ll learn how structured water affects mitochondrial efficiency, how it compares to recovery methods like cold therapy and fasting, and why improved VO₂ max may correlate with a longer lifespan. Dave and Rowena also explore how NanoVi stacks with supplements, nootropics, ketosis, and functional medicine to enhance brain optimization, metabolism, and human performance.

You’ll Learn:

• How structured water boosts mitochondrial function and VO₂ max

• The difference between hydration and energized cellular water

• What happens to your brain and heart rate variability in 20 minutes of NanoVi use

• The link between water structure, protein repair, and recovery

• How biohackers combine NanoVi with fasting, cold therapy, and sleep optimization for faster results

• Why stronger mitochondrial communication can extend lifespan and upgrade cognitive function

They explore how structured water, mitochondrial repair, and recovery science intersect to create a smarter approach to health and longevity. You’ll also learn how optimizing cellular communication, oxygen efficiency, and stress resilience can accelerate healing, improve focus, and extend lifespan.

This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging.

Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience,

Episode description

Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR

You’ll Learn:

• How structured water boosts mitochondrial function and VO₂ max

• The difference between hydration and energized cellular water

• What happens to your brain and heart rate variability in 20 minutes of NanoVi use

• The link between water structure, protein repair, and recovery

• How biohackers combine NanoVi with fasting, cold therapy, and sleep optimization for faster results

• Why stronger mitochondrial communication can extend lifespan and upgrade cognitive function

Mindsip insights from this episode:

Enhance cerebral blood flow with NanoV for cognitive health

Research indicates that using the NanoV can improve cerebral blood flow by 12%, a key factor for cognitive function and preventing dementia.

#blood-flow

#device

Boost mitochondrial connectivity with daily NanoV use

A pilot study using the M-Screen test showed daily NanoV use increased mitochondrial connectivity by 12%, improving how they function as a power grid.

#device

#mitochondria

Pre-treat with resilience machine to enhance protein stability

The device is framed as a 'resilience machine' because pre-treating before a stressful event makes proteins more stable and resistant to damage.

#device

#resilience

Stack NanoV and hydrogen for oxidative damage repair

You can use a double cannula to breathe from both a NanoV and a molecular hydrogen machine simultaneously to repair oxidative damage while also scavenging free radicals.

#biohacking

#hydrogen

Pre-treat with NanoV to reduce lactate build-up by 17%

Pre-treating with NanoV before a workout can reduce performance-limiting lactate by 17%, according to a double-blind, placebo-controlled study.

#device

#lactate

Breathe with NanoV to rapidly reduce stress index

Breathing from the NanoV for just 15 minutes can lead to a 45% drop in the stress index, with the effect starting around the seven-minute mark.

#device

#stress

Increase VO2 max by 7.8% in one session with NanoV device

A single session of breathing from the NanoV device can increase your VO2 max by an average of 7.8%.

#device

#VO2-max

Utilize NanoV device to create ordered water for cellular energy

The NanoV device uses specific electromagnetic wavelengths to create 'ordered water' from humidity, which transfers energy to support protein folding in your cells.