Biohacking Stress & Burnout – Dr. Aditi Nerurkar

Dave Asprey

Apr 23, 2024

Episode description

Managing your stress effectively and building resilience just got easier with Dr. Aditi Nerurkar's guidance on The Human Upgrade. This episode tackles 'toxic resilience,' revealing its impacts on health and well-being. You'll gain insights into the HPA axis—the body's command center for stress response—and learn practical techniques to turn stress into a growth tool. Dr. Aditi introduces the 'Rule of Two,' a simple yet powerful approach to adapting to stress and shows how neuroplasticity can retrain your brain for better stress management. You'll also discover tips for setting digital boundaries, fostering gratitude, managing a full email inbox, and understanding the connections between stress management and longevity. It's all about taking actionable steps toward a more resilient, empowered life.



Timestamp Highlights:

(00:01:21) - The Pressures of the Pandemic and the Surge in Stress 

(00:02:08) - Introducing Dr. Aditi Nerurkar and Her Journey Through Burnout 

(00:05:06) - The Concept of 'Toxic Resilience' and Sustainable Stress Management 

(00:10:16) - The Physiological Responses to Stress and the HPA Axis 

(00:12:12) - Transforming Stress from Maladaptive to Adaptive 

(00:17:16) - The Importance of Understanding Personal Stress Thresholds 

(00:21:06) - Empowering Change and Managing Internal Alerts 

(00:25:15) - The 'Rule of Two' in Stress Adaptation 

(00:32:21) - The Role of Neuroplasticity in Resilience 

(00:37:13) - Combining Conventional Medicine with Stress Management Techniques 

(00:39:29) - How Dr. Nerurkar Achieves an 'Inbox Zero' Lifestyle 

(00:40:59) - The Connection Between Stress Management and Longevity 



Sponsors 

 

Resources 



See Privacy Policy at https://art19

Episode description

Managing your stress effectively and building resilience just got easier with Dr. Aditi Nerurkar's guidance on The Human Upgrade. This episode tackles 'toxic resilience,' revealing its impacts on health and well-being. You'll gain insights into the HPA axis—the body's command center for stress response—and learn practical techniques to turn stress into a growth tool. Dr. Aditi introduces the 'Rule of Two,' a simple yet powerful approach to adapting to stress and shows how neuroplasticity can retrain your brain for better stress management. You'll also discover tips for setting digital boundaries, fostering gratitude, managing a full email inbox, and understanding the connections between stress management and longevity. It's all about taking actionable steps toward a more resilient, empowered life.



Timestamp Highlights:

(00:01:21) - The Pressures of the Pandemic and the Surge in Stress 

(00:02:08) - Introducing Dr. Aditi Nerurkar and Her Journey Through Burnout 

(00:05:06) - The Concept of 'Toxic Resilience' and Sustainable Stress Management 

(00:10:16) - The Physiological Responses to Stress and the HPA Axis 

(00:12:12) - Transforming Stress from Maladaptive to Adaptive 

(00:17:16) - The Importance of Understanding Personal Stress Thresholds 

(00:21:06) - Empowering Change and Managing Internal Alerts 

(00:25:15) - The 'Rule of Two' in Stress Adaptation 

(00:32:21) - The Role of Neuroplasticity in Resilience 

(00:37:13) - Combining Conventional Medicine with Stress Management Techniques 

(00:39:29) - How Dr. Nerurkar Achieves an 'Inbox Zero' Lifestyle 

(00:40:59) - The Connection Between Stress Management and Longevity 



Sponsors 

 

Resources 



See Privacy Policy at https://art19

Mindsip insights from this episode:

Prioritize stress management over weight loss for better health

For the first time, more people are seeking help to manage stress than for weight loss. This shift highlights how stress has become the top health concern, even above goals like losing weight.

Establish healthy boundaries to cultivate true resilience

Real resilience isn't about pushing yourself non-stop or ignoring your limits. It's about setting healthy boundaries, allowing yourself to say no, and leading with self-compassion for the long game.

Cultivate curiosity and a youthful mindset to slow aging

Feeling curious and choosing to see yourself as young and energetic can actually influence your body’s biology. Studies show that your mindset about age and learning keeps you feeling and acting younger, possibly for much longer.

Utilize expressive writing to heal stress and improve well-being

Writing freely about tough or painful experiences for a few days in a row helps your mind process and release stress. This tool can improve mood, sleep, and even physical health.

Practice daily gratitude to shift focus and boost happiness

Writing down five things you’re grateful for every day can shift your brain’s focus from negative to positive. Over time, this habit reduces stress and helps you feel happier and more resilient.

Prioritize monotasking to reduce stress and enhance focus

Focusing on one thing at a time (monotasking) instead of juggling many tasks at once reduces mental overload and stress. Taking short breaks between tasks helps your brain process and remember more.

Establish digital boundaries to enhance calm and sleep

Keeping your phone out of arm's reach, especially in the morning and before bed, lowers stress and helps you sleep better. Simple boundaries like turning off notifications or using an old-school alarm clock make a big difference.

Identify personal stress limits to optimize performance

Everyone has a different 'wall' when it comes to stress limits, and it moves over time. Learning where your wall is helps you push yourself for short bursts, like in a workout, without burning out.

Transform bad stress into healthy growth opportunities

Not all stress is harmful—there’s healthy stress (like excitement from travel or new projects) and bad stress that drags you down. The goal is to turn bad, constant stress into manageable, healthy stress that helps you grow.

Rewire your brain to enhance resilience and stress management

No matter your age or past, your brain is able to change and adapt through new habits and experiences. This means it’s never too late to become more resilient or manage stress better.

Make two small changes for lasting healthy habits

Lasting healthy habits come from making just two small changes at a time and giving yourself about eight weeks to let them stick. Trying to change too much at once overwhelms your brain and usually leads to failure.

Recognize inability to disconnect as modern burnout symptom

A key sign of modern burnout is the inability to disconnect from work, not just feeling tired or unmotivated. This makes it harder to notice burnout in ourselves and others because it doesn't always look like old-school exhaustion.

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© Mindsip 2025 – Made with ❤ in Vilnius