Encore: The Shocking Truth About Ozempic & The Effects It Has On The Body | Calley Means & Dr. Tyna Moore

Mark Hyman

Dec 25, 2024

Episode description

Like most things in life, when it comes to optimizing metabolic health, a nuanced perspective can help. Rather than viewing it as a black-and-white issue, we can take into consideration the big-picture social context we’re facing that encourages ultra-processed foods, obesity, and lifelong medication as well as the micro-level of what people are experiencing as individuals and understanding how to help them when all else fails. 

Today I’m thrilled to sit down with Dr. Tyna Moore and Calley Means for a grounded discussion that explores both sides of the spectrum, and everything in between. 

In this episode, we discuss:

  • The controversial discussion of GLP-1 agonists like Ozempic, weighing the pros and cons of these new drugs in treating obesity and metabolic crises (3:34)

  • Challenging the notion of treating obesity with drugs like Ozempic (10:35)

  • An unsettling revelation about the push for using Ozempic in children (12:04)

  • Digging deeper into GLP-1 research and some of the benefits (32:51)

  • Why are children being born metabolically challenged? (41:11)

  • Dr. Moore’s approach to using peptides with her patients and for her own crippling pain, and what they’ve seen (45:19)

  • How our current healthcare system lacks policies and support for behavior change (1:27)

While there are always differing views, we know for sure that our food and drug policies aren’t serving the best interests of creating sustainable, empowered health for the masses. I hope you’ll tune in to hear more from this comprehensive and lively discussion.

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

Sign Up for Dr. Hyman’s Weekly Longevity Journal

This episode is brought to you by Rupa Health, BIOptimizers, Pique, and Big Bold Health.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Don’t let stress take over your holidays. Try Magnesium Breakthrough from BiOptimizers. Head to Bioptimizers.com/Hyman and use code HYMAN10 to save 10%.

Head over to PiqueLife.com/Hyman20 and get up to 20% off + a complimentary beaker and rechargeable frother.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood. Head to Bigboldhealth.com and use code DrHyman30.

Episode description

Like most things in life, when it comes to optimizing metabolic health, a nuanced perspective can help. Rather than viewing it as a black-and-white issue, we can take into consideration the big-picture social context we’re facing that encourages ultra-processed foods, obesity, and lifelong medication as well as the micro-level of what people are experiencing as individuals and understanding how to help them when all else fails. 

Today I’m thrilled to sit down with Dr. Tyna Moore and Calley Means for a grounded discussion that explores both sides of the spectrum, and everything in between. 

In this episode, we discuss:

  • The controversial discussion of GLP-1 agonists like Ozempic, weighing the pros and cons of these new drugs in treating obesity and metabolic crises (3:34)

  • Challenging the notion of treating obesity with drugs like Ozempic (10:35)

  • An unsettling revelation about the push for using Ozempic in children (12:04)

  • Digging deeper into GLP-1 research and some of the benefits (32:51)

  • Why are children being born metabolically challenged? (41:11)

  • Dr. Moore’s approach to using peptides with her patients and for her own crippling pain, and what they’ve seen (45:19)

  • How our current healthcare system lacks policies and support for behavior change (1:27)

While there are always differing views, we know for sure that our food and drug policies aren’t serving the best interests of creating sustainable, empowered health for the masses. I hope you’ll tune in to hear more from this comprehensive and lively discussion.

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

Sign Up for Dr. Hyman’s Weekly Longevity Journal

This episode is brought to you by Rupa Health, BIOptimizers, Pique, and Big Bold Health.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Don’t let stress take over your holidays. Try Magnesium Breakthrough from BiOptimizers. Head to Bioptimizers.com/Hyman and use code HYMAN10 to save 10%.

Head over to PiqueLife.com/Hyman20 and get up to 20% off + a complimentary beaker and rechargeable frother.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood. Head to Bigboldhealth.com and use code DrHyman30.

Mindsip insights from this episode:

Access compounded GLP-1 peptides for significant cost savings

Compounded versions of GLP-1 peptides like semaglutide can be legally obtained from special pharmacies for a fraction of the brand-name cost, potentially costing a few hundred dollars a year versus nearly $20,000.

Cycle GLP-1 peptides to maintain benefits without dependency

Instead of lifelong continuous use, GLP-1 peptides can be cycled on and off, such as one week off per month, to maintain benefits without constant dependency once metabolically optimized.

Utilize GLP-1 peptides to alleviate autoimmune pain

A doctor shares that she personally microdoses a GLP-1 peptide not for weight loss, but to successfully mitigate crippling pain from her psoriatic arthritis.

Utilize tax-free dollars for health expenses

Companies like Truemed can help you use pre-tax HSA/FSA funds to pay for healthy food, gym memberships, and supplements if a doctor provides a letter of medical necessity.

Address GLP-1 deficiency to regain appetite control

The inability to control appetite and weight may stem from a 'GLP-1 deficiency,' a state potentially caused by our modern environment, gut damage, or even specific genetic mutations.

Explore GLP-1 peptides for heart healing and neuroinflammation reduction

Beyond weight management, GLP-1 peptides are being studied for their regenerative potential in healing heart tissue, reversing heart failure, and reducing neuroinflammation linked to Alzheimer's and Parkinson's.

Manage dosing to mitigate GLP-1 drug side effects

The severe side effects of GLP-1 drugs, like nausea and muscle loss, are often a dosing and management issue, not an inherent flaw of the peptide itself.

Microdose pharmaceuticals for unique therapeutic benefits

Microdosing pharmaceuticals like Prozac or statins can produce a different mechanism of action and therapeutic benefit compared to the drug's effect at a standard macro dose.

DOWNLOAD THE APP

Unlock the wisdom of longevity

DOWNLOAD THE APP

Unlock the wisdom of longevity

DOWNLOAD THE APP

Unlock the wisdom of longevity

Unlock the wisdom of longevity

© Mindsip 2025 – Made with ❤ in Vilnius

Unlock the wisdom of longevity

© Mindsip 2025 – Made with ❤ in Vilnius