How To Not Fall For USELESS Supplements!

Brad Stanfield

Jun 30, 2024

Episode description

How do you know which supplements have proven benefits and are worth taking, versus other supplements which are a waste of money and possibly harmful to our health?

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Here are the links to the research papers referenced in the video:
https://www.sciencedirect.com/science/article/pii/S0925443923001813
https://www.sportmanitoba.ca/https-www-sportmanitoba-ca-sport-science-report-training-energy-systems/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366693/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660611/
https://www.nature.com/articles/s41467-024-49092-5
https://www.sciencedirect.com/science/article/pii/S0735109718345601?via%3Dihub
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345839/
https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.12767

Video edited by Troy Young

The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.

Mindsip insights from this episode:

Take daily multivitamins to enhance cognition

The large-scale COSMOS-Mind study showed that daily multivitamin and mineral supplements resulted in a statistically significant benefit for global cognition over a three-year period.

Focus on functional outcomes over biological age claims

Supplements like Calcium Alpha-Ketoglutarate (AKG) may claim to reduce biological age, but this lab measurement is not a functional outcome like improved strength or walking speed.

Question statistical validity of Nicotinamide Riboside study results

A recent Nicotinamide Riboside study used a less stringent 90% confidence interval to show a positive result, which would not have been statistically significant under the standard 95% confidence interval.

#research

Evaluate long-term safety of Nicotinamide Riboside due to niacin risks

Since Nicotinamide Riboside (a form of Vitamin B3) may be converted to niacin, and high-dose niacin is linked to a 10% increased risk of death, its long-term safety is uncertain.

#risk

#supplement

Choose creatine for proven safety and efficacy

Creatine is an example of a supplement that is worth taking because it meets all five criteria for safety, efficacy, and high-quality evidence.

#creatine

#supplement

Question SIRT6 activator supplements' safety and effectiveness due to lack of human trials

Popular Sirtuin 6 (SIRT6) activator supplements are marketed with mice studies and blog posts, but currently lack a single human randomized controlled trial to prove safety or effectiveness.

#research

#supplement

Insist on human randomized controlled trials for supplement claims

Claims about a supplement must be backed by human randomized controlled trials published in peer-reviewed journals, not by studies on mice or single cells.