MDMA Therapy Without the Drugs? How Vibration Hacks Your Brain for Neuroplasticity | Dave Rabin

Dave Asprey

Mar 14, 2025

Episode description

What do vibrations and the psychedelic experience have in common?

MDMA therapy is revolutionizing mental health treatment, helping people overcome PTSD, anxiety, and emotional trauma with unprecedented success. But what if you could tap into those same powerful benefits—without taking a single drug?

It turns out your brain responds to more than just chemistry. Vibration, frequency, and rhythm have been shaping human consciousness for millennia—from ancient chanting rituals to modern neuroscience breakthroughs. Could the right vibrations unlock the same neuroplasticity and healing pathways as psychedelics?

In this episode, Dave Asprey sits down with Dr. Dave Rabin, a neuroscientist, psychiatrist, and psychedelic researcher, to explore how vibrations can rewire your brain, enhance neuroplasticity, and even mimic the effects of MDMA therapy. Dr. Rabin’s work led to the creation of Apollo Neuro, a wearable device that taps into your nervous system’s natural ability to regulate stress, boost focus, and accelerate recovery—without pharmaceuticals.

What You’ll Discover in This Episode:

• How specific vibrations trigger deep relaxation and neuroplasticity

• Why MDMA therapy works—and how vibration-based tech can simulate it

• The surprising science behind music, frequency, and altered states

• How Apollo Neuro enhances sleep, focus, and emotional resilience

• The overlooked role of heart rate variability in longevity and health

• Why stress is the biggest obstacle to healing—and how to override it

**Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%**

Resources:

• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

• Apollo Neuro Instagram: https://www.instagram.com/apolloneuro/?hl=en

• Apollo Neuro Website: https://apolloneuro.com/Dave

• Danger Coffee: https://dangercoffee.com

• Dave Asprey’s Website: https://daveasprey.com

• Dave Asprey’s Linktree:

Episode description

What do vibrations and the psychedelic experience have in common?

What You’ll Discover in This Episode:

• How specific vibrations trigger deep relaxation and neuroplasticity

• Why MDMA therapy works—and how vibration-based tech can simulate it

• The surprising science behind music, frequency, and altered states

• How Apollo Neuro enhances sleep, focus, and emotional resilience

• The overlooked role of heart rate variability in longevity and health

• Why stress is the biggest obstacle to healing—and how to override it

**Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%**

Resources:

• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

• Apollo Neuro Instagram: https://www.instagram.com/apolloneuro/?hl=en

• Apollo Neuro Website: https://apolloneuro.com/Dave

• Danger Coffee: https://dangercoffee.com

• Dave Asprey’s Website: https://daveasprey.com

• Dave Asprey’s Linktree:

Mindsip insights from this episode:

Create a safe environment to enhance neuroplasticity and learning

Neuroplasticity, or the brain's ability to learn, can only be optimized when the body is in a 'vagal dominant' state of safety, as threat diverts resources away from learning centers.

#neuroplasticity

#vagus-nerve

Enhance sleep quality with Apollo for deeper restorative rest

In clinical trials, Apollo was shown to improve sleep duration as much as the drug Ambien, but unlike the drug, it also increased restorative deep and REM sleep.

#device

#sleep

Utilize Apollo's AI to enhance sleep quality and prevent wake-ups

Apollo's AI can monitor your sleep and deliver vibrations to prevent restlessness from turning into a full wake-up, adding an hour or more of sleep per night for some users.

#AI

#sleep

Adjust intensity of Apollo's vibrations as sensitivity increases

Unlike many substances, the body becomes more sensitive to Apollo's vibrations over time, meaning users often require lower intensity for the same effect.

#biohacking

#device

Achieve over 90% success in kids with ADHD using Apollo

In clinical pilots, children with ADHD, autism, and anxiety who used Apollo showed over 90% success rates in improving mood and behavior.

#ADHD

#anxiety

Increase heart rate variability to enhance longevity

A recent study of Blue Zones found that people who live healthily over 100 years old all have higher Heart Rate Variability (HRV) than the general population.

#HRV

#longevity

Maintain low stress to balance unhealthy habits

People in Blue Zones can often tolerate occasional smoking and drinking because their overall low-stress lifestyle mitigates the inflammatory impact of these habits.

#inflammation

#stress

Recognize tunnel vision as a sign of fight-or-flight response

Having tunnel vision is a physical symptom of being in a fight-or-flight state, as the body diverts resources away from open-mindedness to focus on survival.

#nervous-system

#stress

Utilize Apollo device to replicate MDMA therapy's healing effects

The Apollo device was developed to replicate the profound feelings of safety that MDMA therapy induces in the brain, which allows for healing from trauma.