Still Fasting in 2025? Here’s How to Make It Work Better
Dave Asprey
Aug 15, 2025
Episode description
How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell release, direct them to the right tissues, and stack biohacking tools for maximum regeneration. You’ll learn science-backed strategies for boosting mitochondria, enhancing neuroplasticity, and extending longevity through targeted supplements, fasting, and functional medicine techniques.
Watch this episode on YouTube for the full video experience:
https://www.youtube.com/@DaveAspreyBPR
Host Dave Asprey talks with Christian Drapeau, a leading stem cell scientist and founder of STEMREGEN. Christian’s decades of research have transformed our understanding of how stem cells repair the body, reverse damage, and amplify performance. He shares practical protocols to mobilize stem cells, improve microcirculation, and reduce inflammation so your body heals faster, functions better, and stays younger for longer.
You’ll learn:
• How stem cells rebuild muscle, brain, and organ tissue for optimal human performance
• Why fasting rejuvenates bone marrow and increases stem cell effectiveness
• The synergy between PEMF, vibration therapy, cold therapy, and stem cell activation
• How microcirculation and inflammation control improve longevity and recovery
• The best supplements and nutrients to support mitochondria and stem cell health
• How to stack nootropics, ketosis, and brain optimization tools for lasting energy and focus
This is essential listening for anyone serious about biohacking, longevity, human performance, mitochondria health, neuroplasticity, functional medicine, fasting protocols, supplements for recovery, brain optimization, smarter not harder healing, metabolism upgrades, cold therapy stacks, and next-level physical and cognitive resilience
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.
Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.
Keywords: STEMREGEN, biohacking, natural stem cell activation, human performance, longevity, mitochondria, neuroplasticity, fas
Mindsip insights from this episode:
Regenerate bone marrow through fasting
Fasting is one of the only known ways to regenerate bone marrow, which increases the ability of your stem cells to migrate and multiply, making them act younger.
Implement three keys to optimize stem cell healing
For stem cells to work effectively, you need to 1) release them, 2) ensure they can travel via good microcirculation, and 3) reduce systemic inflammation so they can find their target.
Avoid overtraining to preserve stem cell healing potential
Constant, intense exercise may not lead to better longevity because you use up your stem cell healing potential on countless micro-injuries rather than systemic repair.
Train your bone marrow to enhance stem cell release
The more you trigger your body to release stem cells, the better and more efficient your bone marrow becomes at releasing them over time.
Reduce sugar intake to enhance stem cell function
Chronically elevated blood sugar creates advanced glycation end-products (AGEs) that suppress both the release and the function of your body's stem cells.
Utilize vibration plates to boost circulating stem cells
Sitting on a whole-body vibration plate can increase the number of circulating stem cells, likely by mechanically detaching them from the bone marrow.
Stack PEMF with stem cells for enhanced healing
Taking a stem cell-releasing supplement like Stemregen two hours before a PEMF session creates a powerful synergy, as PEMF helps pool the extra stem cells in the targeted area.
Recognize 500-fold variation in circulating stem cells among individuals
The number of circulating stem cells can vary by 500-fold between individuals, a much wider range of physiological normalcy than any other blood marker.
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