The Hidden Risks of Acid Reflux Medications—and What to Do Instead | Dr. Mark Hyman
Mark Hyman
Nov 29, 2024
Mindsip insights from this episode:
Address low stomach acid to alleviate reflux symptoms
Paradoxically, having low stomach acid can cause reflux symptoms because undigested food can lead to digestive issues and pressure that pushes contents upward.
Stop PPIs to break cycle of reflux dependency
Stopping PPIs can cause a rebound hyper-secretion of acid, making reflux symptoms temporarily worse and creating a cycle of dependency.
Avoid PPIs to reduce heart disease risk
A cohort study found that over five years of cumulative exposure to PPIs doubled the risk of heart disease and heart failure compared to non-users.
Limit PPI use to reduce dementia risk
A study published in the journal Neurology found that people using proton pump inhibitors (PPIs) for over four years were at a higher risk of dementia.
Avoid long-term reflux drugs to prevent nutrient deficiencies
Long-term use of common acid-blocking drugs can cause serious nutritional deficiencies by blocking the absorption of vitamin B12, magnesium, and calcium.
Use melatonin to reduce reflux symptoms effectively
Studies have found that taking 3 to 6 milligrams of melatonin daily is as effective as the common drug omeprazole (Prilosec) in reducing reflux symptoms.
Utilize curcumin as an effective alternative to omeprazole for indigestion
A recent trial found that curcumin was as effective as omeprazole, a common proton pump inhibitor, for treating symptoms of indigestion, including reflux.
Beware of reflux risk with GLP-1 agonists like Ozempic
GLP-1 agonists like Ozempic, which slow gastric emptying, may potentially increase the risk of acid reflux.
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