The Keto Cholesterol Study Has Gone HORRIBLY Wrong
Brad Stanfield
Apr 14, 2025
Mindsip insights from this episode:
Understand LDL cholesterol's dose-dependent risk for heart disease
Data from over two million people shows a consistent, dose-dependent, log-linear link between LDL cholesterol exposure and heart disease risk.
Monitor plaque growth in keto diet participants
The plaque progression in the Keto CTA study was significantly faster than in a non-diabetic cohort and alarmingly close to the progression seen in a diabetic cohort.
Challenge online narratives to make informed health choices
The speaker, a clinician, sees patients with very high LDL cholesterol who refuse to address it because of what they see from online influencers.
Identify lean mass hyper-responders in low-carb diets
Lean mass hyper-responders are defined by a triad of high LDL cholesterol, high HDL cholesterol, and low triglycerides in lean individuals on a low-carbohydrate diet.
Expose hidden outcomes in keto study for transparency
The Keto CTA study initially failed to report its primary outcome in written form with statistical analysis, which is considered a massive red flag in research.
Reassess plaque progression estimates to reflect true impact
Researchers estimated plaque would progress by 7 units, but the actual result was 18.8 units, a figure only released after significant social media pressure.
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