
The Most Underrated Weapon Against Heart Disease
Brad Stanfield
May 16, 2025
Mindsip insights from this episode:
Maintain low LDL to prevent arterial blockages
Even if all other risk factors like insulin resistance are perfect, arterial blockages can still develop if LDL cholesterol is above 50-60 mg/dL.
Start combination therapy immediately after heart attack to reduce death risk
Starting combination therapy right after a heart attack, rather than waiting, can reduce the risk of death from heart disease by 64% compared to adding it later.
Leverage statins and ezetimibe for effective cholesterol management
Statins reduce cholesterol production in the liver while ezetimibe reduces its absorption in the gut, making them a powerful synergistic combination.
Utilize low-dose statins for effective LDL reduction with fewer side effects
Low-dose statin therapy provides about 70% of the LDL-lowering effect of a high dose but with a much lower risk of side effects.
Beware keto diet risks for lean mass hyper-responders
So-called 'lean mass hyper-responders' on low-carb diets, despite being otherwise healthy, saw rapid plaque progression in their blood vessels due to sky-high LDL cholesterol.
Get affordable heart medication online for prevention
A three-month supply of Atorvastatin can be purchased for $7.55 and Ezetimibe for $9.49 from the online pharmacy CostsPlusDrugs.com.
Implement preventative drug regimen to maintain low LDL levels
The speaker, a doctor, personally takes a preventative combination of Atorvastatin 20mg and Ezetimibe 10mg while young to keep his LDL levels low.
Debunk low cholesterol myth to clarify health risks
The idea that low cholesterol is dangerous is often a misinterpretation, as chronic illnesses and old age can cause both low cholesterol and high mortality, creating a false correlation.
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