Predicting & Preventing Disease with Precision Medicine | Dr. Jeremy Nicholson

Mark Hyman

2 oct 2024

Episode description

What if we could predict disease before it even starts? In this episode, I’m joined by Dr. Jeremy Nicholson to explore the cutting-edge science of precision medicine and how understanding your unique biology could hold the key to preventing illness. We dive into the future of diagnostics, the power of the exposome in shaping your health, and how advancements like gene editing could revolutionize treatment.

In this episode, we discuss:

The emerging field of phenomic medicine
Moving away from one-size-fits-all treatments toward more personalized medical approaches based on individual biology
Long COVID and its impact
The critical role of the microbiome in overall health, immune system function, and its direct influence on diseases
How the exposome, or all of the environmental exposures a person experiences, plays a crucial role in shaping health outcomes
Advanced technologies like metabolic profiling, which can reveal subtle biochemical signals and identify disease risks long before symptoms appear.
How gene-environment interactions drive the development of complex diseases, making personalized medical approaches crucial for effective treatment

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

This episode is brought to you by Rupa Health, Cozy Earth, BIOptimizers, and Neurohacker.

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Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit Bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Decrease your "zombie cells" with Qualia Senolytic. Visit QualiaLife.com/Hyman to get 50% off and use code HYMAN for an additional 15% off your order.

Episode description

In this episode, we discuss:

The emerging field of phenomic medicine
Moving away from one-size-fits-all treatments toward more personalized medical approaches based on individual biology
Long COVID and its impact
The critical role of the microbiome in overall health, immune system function, and its direct influence on diseases
How the exposome, or all of the environmental exposures a person experiences, plays a crucial role in shaping health outcomes
Advanced technologies like metabolic profiling, which can reveal subtle biochemical signals and identify disease risks long before symptoms appear.
How gene-environment interactions drive the development of complex diseases, making personalized medical approaches crucial for effective treatment

View Show Notes From This Episode

Get Free Weekly Health Tips from Dr. Hyman

This episode is brought to you by Rupa Health, Cozy Earth, BIOptimizers, and Neurohacker.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com.

Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit Bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Decrease your "zombie cells" with Qualia Senolytic. Visit QualiaLife.com/Hyman to get 50% off and use code HYMAN for an additional 15% off your order.

Mindsip insights from this episode:

Discover body's natural antiviral production against infections

Researchers have discovered that the human body produces its own antiviral drugs, a new class of cytosine derivatives, as part of an ancient immune response to viral infections.

#antiviral

#immune-system

Prioritize environment and microbiome over genes for health

For most people, the environment and microbiome have far more power in determining future diseases than the human genome itself.

#environment

#microbiome

Recognize limits of 'Churchill genes' in tolerating poor habits

Some people possess resilient 'Churchill genes' that allow them to tolerate poor lifestyle habits like heavy drinking and smoking into old age, but this is not the case for most.

#genetics

#resilience

View aging as a cumulative metabolic journey

Aging can be viewed as the cumulative result of many small 'journeys' in metabolic space where, after each illness, your body never returns to the exact same biological starting point.

#aging

#metabolism

Recognize hidden biochemical abnormalities of occult long Covid

Even if you feel fine after having COVID, 100% of people tested show some long-term, hidden biochemical abnormalities, a phenomenon the speaker calls 'occult long Covid'.

#chronic-disease

#COVID-19

Address tryptophan-kynurenine pathway to combat Long Covid brain fog

The tryptophan-kynurenine pathway is persistently disturbed in Long Covid, leading to brain fog and fatigue by creating neurotoxic byproducts like quinolinic acid.

#cognition

#COVID-19

Monitor ApoB to ApoA1 ratio post-COVID to assess heart disease risk

A COVID-19 infection can dramatically and persistently worsen your ApoB to ApoA1 ratio, a key biomarker that increases your long-term risk for heart attack and stroke.