#1 Way to SUPERCHARGE Glutathione Absorption (Plus Crazy Benefits) With Dr. Nayan Patel
Ben Greenfield
May 16, 2024
Mindsip insights from this episode:
Understand NAC regulation to avoid misleading supplement claims
N-acetylcysteine (NAC) is regulated by the FDA as a drug, so supplements cannot make claims about its effects, such as curing hangovers or improving liver health.
Limit glutamine supplements to protect neurological health
You should avoid taking too much glutamine, especially for neurological health, as the brain naturally produces it as a byproduct of metabolism.
Consider limitations of IV glutathione for long-term benefits
Intravenous (IV) glutathione has a very short response rate, staying in the body for only about 14-15 minutes, making it less effective for achieving long-term metabolic benefits.
Utilize novel twisted glutathione for direct skin absorption
A new form of topical glutathione was created by chemically 'twisting' the tripeptide molecule, making it small enough to be absorbed directly through the skin without breaking down.
Boost glutathione production with cysteine-rich foods
Cysteine is the scarcest glutathione precursor in our diet, so consuming cysteine-rich foods like whey protein and avocados is the best dietary strategy to boost production.
Understand liposomal glutathione breakdown for effective absorption
Studies show that liposomal glutathione often breaks down into its precursor amino acids in the body, which are then used to build new glutathione, rather than being absorbed whole.
Avoid glutathione overdose to prevent reductive stress
Taking too much highly bioavailable glutathione can shift your body from oxidative stress to an unhealthy 'reductive stress' state, which can manifest as skin rashes and itching.
Avoid antioxidants before exercise to maximize hormetic stress benefits
Avoid taking powerful antioxidants like glutathione immediately before exercise or cold plunges, as this can blunt the beneficial inflammatory and hormetic response from the stress.
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