Are Urolithin A Longevity Supplements worth your Money? [New Study]

Episode description

JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 HEALTH AUTONOMY [COURSE]Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomyJOIN THE COMMUNITYJoin my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2EMAIL LIST1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6HIRE ME FOR CONSULTING: Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction0:48 - The Benefits of Urolithin A4:40 - I discourage you..8:15 - Context Matters9:19 - Main Points / Key TakeawaysOther Urolithin A Analysis: https://youtu.be/cJdAlp2new4?si=J08IL1mSoPbhLst1Reference[Study 549] Denk D, Singh A, Kasler HG, et al. Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial. Nat Aging. 2025;5(11):2309-2322. doi:10.1038/s43587-025-00996-xFunding/Conflicts: Public: this trial received public and institutional support for D. Denk and F.R.G. from the Deutsche Forschungsgemeinschaft (DFG; DE 4233/1-1, SFB1292, SFB1479, GRK2336), the German Federal Ministry of Education and Research (BMBF; 01KD2206Q/SATURN3), the European Research Council (Advanced Grant PLASTICAN-101021078), institutional funds from the Georg-Speyer-Haus, the LOEWE Center Frankfurt Cancer Institute funded by the Hessen State Ministry for Higher Education, Research and the Arts, and core funding of the Georg-Speyer-Haus jointly by the German Federal Ministry of Health and the Ministry of Higher Education, Research and the Arts of the State of Hessen, as well as support from the Clinical Trial Center Network of the Universitäres Centrum für Tumorerkrankungen (UCT) Frankfurt; Non-Profit: D. Denk was supported by the Mildred-Scheel Nachwuchszentrum Frankfurt funded by the German Cancer Aid (Deutsche Krebshilfe); Industry: UA (Mitopure) and study funds were provided by Amazentis SA, which co-designed this investigator-initiated trial but had no role in data collection, analysis, decision to publish or manuscript preparation, and several authors report industry-related competing interests, including employment of A.S., D. D’Amico and J.F. by Amazentis SA, C.R. serving as president and delegate of the board of Amazentis SA, consulting fees to F.R.G. from Amazentis, travel compensation to D. Denk from Amazentis and AbbVie, and restrictions on commercial use of SCENITH owing to a pending patent application (PCT/EP2020/WO2020212362A1 to R.J.A.), while the remaining authors declare no competing interests related to this study.CRITIQUES, RULES, AND NOTESBe aware of the following rules before posting comments:- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES:If your comment is rude, you will be banned.If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!). Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes. #urolithina #timeline

Episode description

JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 HEALTH AUTONOMY [COURSE]Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomyJOIN THE COMMUNITYJoin my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2EMAIL LIST1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6HIRE ME FOR CONSULTING: Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction0:48 - The Benefits of Urolithin A4:40 - I discourage you..8:15 - Context Matters9:19 - Main Points / Key TakeawaysOther Urolithin A Analysis: https://youtu.be/cJdAlp2new4?si=J08IL1mSoPbhLst1Reference[Study 549] Denk D, Singh A, Kasler HG, et al. Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial. Nat Aging. 2025;5(11):2309-2322. doi:10.1038/s43587-025-00996-xFunding/Conflicts: Public: this trial received public and institutional support for D. Denk and F.R.G. from the Deutsche Forschungsgemeinschaft (DFG; DE 4233/1-1, SFB1292, SFB1479, GRK2336), the German Federal Ministry of Education and Research (BMBF; 01KD2206Q/SATURN3), the European Research Council (Advanced Grant PLASTICAN-101021078), institutional funds from the Georg-Speyer-Haus, the LOEWE Center Frankfurt Cancer Institute funded by the Hessen State Ministry for Higher Education, Research and the Arts, and core funding of the Georg-Speyer-Haus jointly by the German Federal Ministry of Health and the Ministry of Higher Education, Research and the Arts of the State of Hessen, as well as support from the Clinical Trial Center Network of the Universitäres Centrum für Tumorerkrankungen (UCT) Frankfurt; Non-Profit: D. Denk was supported by the Mildred-Scheel Nachwuchszentrum Frankfurt funded by the German Cancer Aid (Deutsche Krebshilfe); Industry: UA (Mitopure) and study funds were provided by Amazentis SA, which co-designed this investigator-initiated trial but had no role in data collection, analysis, decision to publish or manuscript preparation, and several authors report industry-related competing interests, including employment of A.S., D. D’Amico and J.F. by Amazentis SA, C.R. serving as president and delegate of the board of Amazentis SA, consulting fees to F.R.G. from Amazentis, travel compensation to D. Denk from Amazentis and AbbVie, and restrictions on commercial use of SCENITH owing to a pending patent application (PCT/EP2020/WO2020212362A1 to R.J.A.), while the remaining authors declare no competing interests related to this study.CRITIQUES, RULES, AND NOTESBe aware of the following rules before posting comments:- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES:If your comment is rude, you will be banned.If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!). Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes. #urolithina #timeline