Chronic Stress Is Aging Your Body Faster Than Smoking (Here's How To Reverse It) | Dr Elissa Epel

Rangan Chatterjee

Jun 24, 2026

Episode description

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Could the stress you barely notice be more harmful than you think? Most of us know chronic stress is bad for us, but few of us realise how deep that damage can go – or how much power we have to reverse it. In this enlightening episode, I speak with one of the world's leading stress researchers Dr Elissa Epel, a professor of psychiatry at the University of California, to explore the latest science of stress, ageing – and why deep rest may be the remedy we’re overlooking.

Elissa's research as a health psychologist reveals that chronic stress can age our immune systems by as much as 10 years. But with the right habits we can activate the repair mechanisms that slow and even reverse that process. We talk about her framework of four mind states – red, yellow, green and blue – outlined in her book, The Seven-Day Stress Prescription. I find it one of the most useful tools for understanding our place on the stress spectrum at any given moment. We explore why so many of us have lost the ability to relax, the importance of deep rest for cellular repair, and the evening habits that transform the quality of your sleep.

We also discuss the very latest in wearable technology and the metrics Elissa believes are worth tracking. She makes the distinction between monitoring daily stress levels and the tech that can now track longer-term trends. And she shares her experience with continuous glucose monitoring and what it revealed to her about the relationship between stress, sleep and metabolic health.
I loved hearing about the Big Joy Project, Elissa’s ongoing study of around 20,000 people, finding that small, simple acts of kindness and connection can shift our emotions over the course of a week and make us more altruistic and prosocial. At a time when the world can feel divided, I think that matters enormously.

Finally, we explore how changing the story you tell yourself about a stressful situation, current or past, can transform your physiological response. This reframing is something I’ve learned to do and find endlessly empowering. Our perception is not just a mental experience. It shapes our biology.
Elissa is an open-hearted communicator, whose generosity comes across in everything she shares with us here. Whether you struggle with overwhelm, or you suspect you’re more stressed than you realise, I know this conversation has advice you’ll want to take on board.

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Find out more about Dr Epel:
Website https://www.elissaepel.com/
Instagram https://www.instagram.com/elissa.epel/?hl=en
Twitter https://twitter.com/Dr_Epel
Facebook https://www.facebook.com/TelomereEffect
YouTube https://www.youtube.com/channel/UCirLcEfBEaIynGDwZaJvdaQ

Dr Epel’s books:
The Telomere Effect:The New Science of Living Younger UK https://amzn.to/4aceSFv US https://amzn.to/4eXgiq0
The Stress Prescription: Seven Days to More Joy and Ease UK https://amzn.to/4gz9L68 US https://amzn.to/4oEY6VD

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DISCLAIMER: The content in the podcast and on this webpage is not intended to constitute or be a substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

Mindsip insights from this episode:

Enhance neighborhood characteristics to improve telomere length

Studies show that your neighborhood's characteristics, such as green space and feelings of safety, are a predictor of your telomere length in adulthood.

Practice slow daytime breathing to enhance nighttime sleep

Practicing very short periods of slow breathing during the day can improve your vagal tone and allow you to reach deeper states of rest during sleep at night.

Identify and manage four mind states of stress

Stress can be categorized into four states: Red (acute stress), Yellow (subtle chronic stress), Green (relaxation), and Blue (deep, restorative rest).

Boost telomerase to reverse stress-induced aging

Lifestyle changes can boost the telomerase enzyme, which can repair and lengthen telomeres, potentially reversing years of stress-induced cellular aging.

Ensure safety to achieve deep restorative rest

To enter the most restorative 'Blue Mind' state, our bodies first need to perceive physical and social safety in our environment.

Utilize Apollo Neuro for calming vibrations and nervous system management

The Apollo Neuro is a wearable device that provides gentle vibrations to the body, which can feel calming and help manage the nervous system.

Practice mindful eating for better outcomes in future children

A study found that pregnant women taught mindful eating had better metabolic health, and their children showed more stress resilience eight years later.

Reframe stressors as challenges to enhance recovery

Viewing a stressor as a challenge rather than a threat changes your body's physiological response to be healthier and promotes faster recovery.

Shift gene expression through multi-day meditation retreats

During multi-day meditation retreats, the body's gene expression shifts to create more proteins for cell restoration, like telomerase, and fewer for immunity and stress.

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