Dementia Rates PLUNGED in Study of 1 Million People
Brad Stanfield
Nov 6, 2025
Mindsip insights from this episode:
Enhance memory performance in older adults with creatine supplements
Creatine supplements, often used for muscle building, have been shown in a meta-analysis to improve memory performance, with a particularly strong effect in older adults.
Take daily multivitamins to slow brain aging by two years
Taking a daily multivitamin and mineral supplement was found in one trial to be equivalent to reducing the aging of the brain by two years.
Simulate lifelong statin use to reduce dementia risk by 76%
A Mendelian randomization trial, which mimics lifelong statin use through genetics, found a 76% relative risk reduction for dementia.
Mitigate dementia risk by addressing hearing loss with aids
For every 10 decibels of hearing loss your dementia risk goes up by 16%, but using hearing aids can significantly lower this risk.
Use TMG to lower homocysteine and prevent Alzheimer's
The supplement TMG may help prevent Alzheimer's disease by lowering high levels of homocysteine, an amino acid strongly linked to the disease.
Treat midlife depression to lower dementia risk by 30%
Depression in midlife more than doubles the risk of developing dementia later on, but treatment can reduce this risk by about 30%.
Incorporate microvitamin plus for optimal supplementation
The speaker personally takes a powder called microvitamin plus, which combines a multivitamin, creatine, and TMG.
Evaluate cholesterol-lowering mechanisms for dementia risk reduction
The mechanism used to lower LDL cholesterol might be as important as the lowering itself, as powerful PCSK9 inhibitors showed no clear dementia risk reduction in one study.
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