How to Optimize Your Brain for WORK: Achieving Hyper-Efficiency with Dr. Mithu Storoni

Dave Asprey

Nov 12, 2024

Episode description

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless

In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can lead to improved cognitive efficiency and resilience in high-stress environments. 

Get ready to discover actionable science-backed hacks for enhancing work productivity and maintaining focus—even in the face of constant distractions. Dr. Storoni also explains how optimizing your breathing rhythm, managing your brain’s arousal state, and tapping into the natural flow of ultradian rhythms can dramatically improve your mental output. 

Whether you’re looking to elevate your workflow, supercharge your mental performance, or unlock the science of hyper-efficiency, this episode delivers essential strategies to cultivate a high-performing mind for work and beyond. Tune in to understand how the latest neuroscience can transform how you think, focus, and excel every day. 



Sponsors 

-Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. 

-Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. 



Resources: 

• Dr. Mithu Storoni’s Websitehttps://www.mithustoroni.com 

Hyper Efficient: Optimize Your Brain to Transform the Way You Work by Dr. Mithu Storonihttps://www.hachettebookgroup.com/titles/mithu-storoni/hyperefficient/9780316566933/ 

• Dr. Mithu Storoni on Facebookhttps://www.facebook.com/drmithustoroni/ 

• Dr. Mithu Storoni’s LinkedInhttps://www.linkedin.com/in/mithu-storoni-0488872a/ 

• Dave Asprey’s Websitehttps://daveasprey.com 

• Dave Asprey’s Book: Smarter Not Harder

Episode description

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless

In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can lead to improved cognitive efficiency and resilience in high-stress environments. 

Get ready to discover actionable science-backed hacks for enhancing work productivity and maintaining focus—even in the face of constant distractions. Dr. Storoni also explains how optimizing your breathing rhythm, managing your brain’s arousal state, and tapping into the natural flow of ultradian rhythms can dramatically improve your mental output. 

Whether you’re looking to elevate your workflow, supercharge your mental performance, or unlock the science of hyper-efficiency, this episode delivers essential strategies to cultivate a high-performing mind for work and beyond. Tune in to understand how the latest neuroscience can transform how you think, focus, and excel every day. 



Sponsors 

-Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. 

-Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. 



Resources: 

• Dr. Mithu Storoni’s Websitehttps://www.mithustoroni.com 

Hyper Efficient: Optimize Your Brain to Transform the Way You Work by Dr. Mithu Storonihttps://www.hachettebookgroup.com/titles/mithu-storoni/hyperefficient/9780316566933/ 

• Dr. Mithu Storoni on Facebookhttps://www.facebook.com/drmithustoroni/ 

• Dr. Mithu Storoni’s LinkedInhttps://www.linkedin.com/in/mithu-storoni-0488872a/ 

• Dave Asprey’s Websitehttps://daveasprey.com 

• Dave Asprey’s Book: Smarter Not Harder

Mindsip insights from this episode:

Achieve flow state to enhance efficiency and output

The flow state may be a state of hyper-efficiency where your attention and reward networks synchronize, increasing output without using more energy.

Utilize locus coeruleus to regulate brain function modes

A tiny brain region called the locus coeruleus, or 'blue dot,' acts like a gear shift, setting the entire brain's pace into one of three modes of functioning.

Monitor retinal nerve fiber thickness to assess brain health

Your eyes are a direct extension of the brain, and factors like retinal nerve fiber thinning can be a proxy for overall brain degeneration.

Implement cyclical ketosis for optimal brain health

Unending ketosis is detrimental to glial cells because they thrive on glucose, making cyclical ketosis a better strategy for brain health and metabolic flexibility.

Show affection to boost astrocyte levels in the brain

Research on mice by Professor Marian Diamond suggested that showing them affection by stroking them appeared to increase the levels of their brain's astrocytes.

Support neurons with astrocytes for enhanced brain function

Einstein's brain had more astrocytes, which are housekeeper cells that support neurons by providing ketones and clearing waste, rather than more neurons.

Work in 90-minute ultradian cycles to boost focus

Your attention naturally waxes and wanes in 90-minute ultradian cycles during the day, so taking a break after about 90 minutes of focused work replenishes brain resources.

Breathe 5-6 times per minute to activate vagus nerve

Breathing at a resonance frequency of five to six breaths per minute is optimal for activating the vagus nerve and keeping your brain in a balanced state.

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