How to Relentlessly Prioritize Your Life – Jesse Itzler

Dave Asprey

Jan 4, 2024

Episode description

Today, we take a look into the mindset and habits of successful entrepreneurs and mastering the art of organization for success, topics that today’s guest has totally mastered. 

Jesse Itzler has an impressive background with a bachelor's degree from American University and a further degree in justice, law, and society. His resume as an entrepreneur is also quite impressive, co-founding Marquis Jet, the world's largest private jet card company, which was later sold to Berkshire Hathaway/NetJets. Beyond this, he's partnered with Zico coconut water, selling it to The Coca-Cola Company, and has ventured into the music industry, co-writing Billboard Top 100 hits and co-founding Alphabet City Sports Records. 

Jesse is also an acclaimed triathlete and author, with his book, Living with a Seal, becoming a New York Times bestseller.

As we step into the early days of 2024, this episode is all about providing you with clear, direct methods to upgrade your life across various facets—work, fitness, and personal development. Tune in as I compare and contrast my organizational methods with Jesse's, the goal being to introduce you to strategies that resonate with you and align with your personality. 

You'll gain insights into how Jesse efficiently prioritizes his calendar and the skills needed to outperform competition when you’re starting out in business. We also explore habits and tools for staying physically and mentally young, our favorite biohacks, my personal excitement in the field of longevity, and ways to structure your life for maximum return on investment, both in terms of monetary success and happiness. 

While our methods differ in some areas, our objective is the same: to live a life with minimal regrets, whether you reach 80 or 180 years old. Join us as we discuss the habits of successful entrepreneurs—both from our experience and learning from others at the top of their game—and discover practical ways to implement these lessons into your life.

(00:00:20) The Secret to Jesse’s Success in Business & Triathlons

(00:05:10) How Jesse Organizes His Life & Implements New Habits

(00:22:49) Structuring Support Systems & Early Hires

(00:32:41) Lessons From Living With a Seal & Monks

(00:48:19) What Biohacks Dave Is Most Excited About

(00:54:21) How To Organize Your Time Efficiently

(01:01:54) The Mindset & Habits of Successful Entrepreneurs

(01:10:34) The Recipe for a Fulfilling Life

(01:18:46) Dave’s Top Tools for Longevity

Resources

Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books 

Website: jesseitzler.com

Instagram: @jesseitzler

T

Episode description

Today, we take a look into the mindset and habits of successful entrepreneurs and mastering the art of organization for success, topics that today’s guest has totally mastered. 

Jesse Itzler has an impressive background with a bachelor's degree from American University and a further degree in justice, law, and society. His resume as an entrepreneur is also quite impressive, co-founding Marquis Jet, the world's largest private jet card company, which was later sold to Berkshire Hathaway/NetJets. Beyond this, he's partnered with Zico coconut water, selling it to The Coca-Cola Company, and has ventured into the music industry, co-writing Billboard Top 100 hits and co-founding Alphabet City Sports Records. 

Jesse is also an acclaimed triathlete and author, with his book, Living with a Seal, becoming a New York Times bestseller.

As we step into the early days of 2024, this episode is all about providing you with clear, direct methods to upgrade your life across various facets—work, fitness, and personal development. Tune in as I compare and contrast my organizational methods with Jesse's, the goal being to introduce you to strategies that resonate with you and align with your personality. 

You'll gain insights into how Jesse efficiently prioritizes his calendar and the skills needed to outperform competition when you’re starting out in business. We also explore habits and tools for staying physically and mentally young, our favorite biohacks, my personal excitement in the field of longevity, and ways to structure your life for maximum return on investment, both in terms of monetary success and happiness. 

While our methods differ in some areas, our objective is the same: to live a life with minimal regrets, whether you reach 80 or 180 years old. Join us as we discuss the habits of successful entrepreneurs—both from our experience and learning from others at the top of their game—and discover practical ways to implement these lessons into your life.

(00:00:20) The Secret to Jesse’s Success in Business & Triathlons

(00:05:10) How Jesse Organizes His Life & Implements New Habits

(00:22:49) Structuring Support Systems & Early Hires

(00:32:41) Lessons From Living With a Seal & Monks

(00:48:19) What Biohacks Dave Is Most Excited About

(00:54:21) How To Organize Your Time Efficiently

(01:01:54) The Mindset & Habits of Successful Entrepreneurs

(01:10:34) The Recipe for a Fulfilling Life

(01:18:46) Dave’s Top Tools for Longevity

Resources

Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books 

Website: jesseitzler.com

Instagram: @jesseitzler

T

Mindsip insights from this episode:

Stop external meetings to protect energy and focus

To protect your energy and focus, stop taking external meetings and instead have people come to you only when absolutely necessary.

Plan your year around a defining goal and mini-adventures

Structure your year around one big defining goal (a "Misogi"), six mini-adventures, and four new quarterly habits to build your "life resume.".

Immerse yourself with masters to deepen learning

The most profound way to learn is to immerse yourself by living with masters in their field, from monks for spirituality to Navy SEALs for mental toughness.

Utilize gene therapy to reverse biological aging

A single, non-permanent gene therapy injection can potentially take nine years off your biological age by teaching your body to make youthful compounds.

Maximize fitness gains with 20 minutes of AI-driven exercise weekly

AI-driven exercise systems can provide better fitness improvements in just 20 minutes a week by optimizing the intensity and recovery signals to the body.

Outsource laundry to focus on building your business

The first task any aspiring entrepreneur should outsource is their laundry, as it's a low-value use of time that could be spent building their business.

Eat fruit at dinner to enhance sleep quality

Contrary to popular advice, eating fruit in the morning can destabilize energy, whereas eating it at dinner can help improve sleep.

Prioritize low aggravation opportunities over high-stress rewards

An evolved entrepreneurial mindset prioritizes opportunities with low aggravation for any reward, rather than the high-stress, high-reward model.

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© Mindsip 2025 – Made with ❤ in Vilnius

Unlock the wisdom of longevity

© Mindsip 2025 – Made with ❤ in Vilnius