
My Anti-Aging Skincare Routine
Bryan Johnson
Jan 9, 2024
Mindsip insights from this episode:
Pause radiofrequency treatment to prevent facial fat loss
A radiofrequency device (Exilis) was paused out of concern it could cause facial fat loss, even when used at the supposedly restorative temperature of 40-42°C.
Microdose Accutane to manage acne from anti-aging therapies
Microdosing Accutane at 40mg twice a week can effectively manage acne caused as a side effect of other anti-aging therapies like Rapamycin.
Use an umbrella to prevent skin damage during peak sun hours
Using an umbrella when walking outside between 10 am and 4 pm is a highly effective, if socially unconventional, way to prevent skin damage.
Embrace paleness to reverse aging damage
The goal is to reverse aging damage, not adhere to cultural norms of having a tan, which means actively trying to be pale by avoiding the sun.
Utilize full-body IPL to rejuvenate skin gene expression
Inspired by a Stanford study, full-body Intense Pulsed Light (IPL/BBL) is used to change the genetic expression of the skin to be dramatically younger.
Measure skin AGEs to assess cardiovascular health
Advanced glycation end products (AGEs) are measured in the skin of the arm to serve as a biomarker for overall cardiovascular health.
Choose Tixel for safe and effective skin treatment
The Tixel device, which uses thermal-mechanical ablation, is now preferred over other lasers and radiofrequency for being both safe and effective.
Choose devices over creams for significant skin improvement
Most topical creams fail to show significant improvement on data-driven skin metrics, making devices like lasers necessary for meaningful change.
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