Prevention Strategies for Neurodegenerative Diseases
Mark Hyman
May 20, 2024
Mindsip insights from this episode:
Reconsider amyloid plaque as bacterial protective biofilm in Alzheimer's
The amyloid plaque seen in Alzheimer's may actually be a protective 'bomb shelter' or biofilm created by bacteria to shield themselves.
Utilize hyperthermia to halt or reverse ALS progression
Hyperthermia, or inducing a controlled fever, is a therapy showing early promise in stopping or even reversing the progression of ALS in some patients.
Reframe Alzheimer's as a systemic disease affecting the brain
The emerging paradigm is that Alzheimer's is not a primary brain disease but rather a systemic disease that affects the brain.
Incorporate HIIT for ApoE4 gene carriers
High-Intensity Interval Training (HIIT) is considered almost necessary for individuals who carry at least one copy of the ApoE4 gene variant.
Implement ketogenic diet for symptomatic Alzheimer's management
A ketogenic diet makes more sense as a therapeutic intervention in the symptomatic phase of Alzheimer's, whereas a Mediterranean diet is better for prevention.
Recognize brain insulin resistance as Type 3 diabetes
You can have insulin resistance in the brain, leading to what's called 'Type 3 diabetes', even if you don't have insulin resistance in the rest of your body.
Identify oral bacteria as potential Alzheimer's trigger
A specific oral bacteria, P. gingivalis, creates a protein called gingipain that may be a neurotoxin and a trigger for neuroinflammation.
Run to boost Brain-Derived Neurotrophic Factor for brain health
Many neuroscientists are runners because it is the fastest way to raise Brain-Derived Neurotrophic Factor (BDNF), which is described as 'Miracle-Gro for the brain'.
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