Cheap, Revolutionary Blood Test can Predict your Alzheimer’s Disease Risk
Physionic
Jan 8, 2026
Episode description
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0:00 - Introduction
0:53 - Why it Matters
2:40 - The Amyloid-Tau Dance
5:29 - GSK3
7:00 - Progression of Disease
8:05 - The Test... put to the Test
9:32 - Where to get the Test
11:23 - Important Considerations before getting the Test
13:09 - How I would Approach This
13:39 - The Anti-Alzheimer's Supplement
References
[1] Kavanagh K. Blood tests are now approved for Alzheimer’s: how accurate are they? Nature. 2025 Oct 30;646:1031-1032
[Study 585] Thijssen EH, La Joie R, Wolf A, et al. Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration. Nat Med. 2020;26(3):387-397. doi:10.1038/s41591-020-0762-2
[Study 586] Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, et al. The amyloid-β pathway in Alzheimer’s disease. Mol Psychiatry. 2021;26:5481-5503. doi:10.1038/s41380-021-01249-0.
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#alzheimersprevention #alzheimerawareness #alzheimersdisease
Mindsip insights from this episode:
Avoid Alzheimer's risk factor test if living optimally
If you already live an optimized life, knowing you are positive for an Alzheimer's risk factor may only add stress without changing your behavior.
Order tau protein test from major labs like Quest Diagnostics and LabCorp
You can order versions of the tau protein test, like the Lumipulse G PTau217, from major labs such as Quest Diagnostics and LabCorp.
Utilize phospho-tau blood test for accurate Alzheimer's diagnosis
The phospho-tau blood test is highly specific for Alzheimer's disease and will not show elevated levels for other forms of dementia.
Utilize lithium to prevent Alzheimer's by blocking GSK3 enzyme
The mineral lithium has evidence backing its ability to prevent Alzheimer's by potently blocking the GSK3 enzyme from damaging tau proteins.
Target GSK3 enzyme to combat Alzheimer's progression
Amyloid plaques trigger an enzyme called GSK3, which then causes the tau protein dysfunction that is a key step in Alzheimer's progression.
Understand age's role in Alzheimer's test result interpretation
A negative Alzheimer's test result for a 60-year-old is a better indication of being in the clear than a negative result for a 40-year-old.
Utilize phospho-tau181 blood test to screen for Alzheimer's with confidence
A new blood test called phospho-tau181 can screen for Alzheimer's with 98% confidence on a negative result, replacing the need for PET scans or spinal taps.
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