The 18 Conversations That CHANGED Us In 2025 | Best of 2025 Part 1

Rich Roll

Dec 22, 2025

Episode description

Part 1 of our annual "Best Of" series is here, a tradition 12 years in the making. We revisit the year's most powerful conversations on longevity, happiness, brain health, consciousness, and what it takes to change. Thank you for an incredible 2025. READ MORE👉🏼http://bit.ly/richroll957
✌🏼🌱 – Rich

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Hi I'm Rich Roll. I'm a vegan ultra-endurance athlete, author, podcaster, public speaker & wellness evangelist. But mainly I'm a dad of four. If you want to know more, visit my website or check out these two the NY Times articles:
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Mindsip insights from this episode:

Transcend rules for personal growth through three levels of knowing

Personal growth involves moving from not knowing the rules (level 1), to following the rules (level 2), to knowing the rules but choosing to transcend them (level 3).

#personal-growth

Balance red meat intake with high fruit and vegetable consumption to mitigate cancer risk

Studies suggesting red meat is safe with high fruit and vegetable intake often use consumption levels below the threshold where cancer risk typically appears.

#cancer

#red-meat

Cultivate Yoyu for forgiveness and well-being

The concept of 'Yoyu' is having an abundance of space in your heart to accept others and respond to hardship, which is a key to forgiveness and well-being.

#emotion

#resilience

Beware muscle loss with GLP-1 drugs to prevent fat gain

While GLP-1 drugs cause rapid weight loss, a significant portion is muscle, and regaining the weight as fat can lead to a higher body fat percentage long-term.

#GLP1

#muscle

Fuel aging brain with lactate from vigorous exercise

Vigorous exercise produces lactate, which crosses the blood-brain barrier to fuel the brain, increase BDNF, and grow new neurons in the hippocampus.

#exercise

#lactate

Choose Momentous Creatine Chews for purity and quality

Momentous Creatine Chews use single-source German Creapure and are NSF certified, avoiding the fillers and sugars found in many mainstream gummy versions.

#creatine

#supplement

Activate organ self-repair with fasting mimicking diet cycles

Cycles of a Fasting Mimicking Diet (FMD) can trigger the body's own regenerative programs, turning on developmental genes to repair damage in organs like the kidneys and pancreas.

#fasting

#regeneration

Recognize masochistic narcissism in high achievers for healthier self-worth

High-functioning people who constantly work and delay pleasure may be 'masochistic narcissists' who derive their self-worth from believing they are the only ones who can do things right.

#narcissism

#self-awareness

Prioritize giving to enhance happiness over self-care

Experiments show people report greater happiness when spending money on others compared to spending it on themselves, challenging the popular focus on self-care.