The Crazy Little Mushroom Extract You've Never Heard Of (CRUSHES Workouts, Amplifies Deep Sleep & Bulletproofs Your Immune System?) With Dr. Scott Sherr

Ben Greenfield

Jun 5, 2025

Episode description

In today’s episode, I sit down with returning guest Dr. Scott Sherr, a board-certified internal medicine physician known for his work in hyperbaric medicine, innovative nootropics, and his role as Chief Operating Officer of Troscriptions, where he developed the infamous precision-dosed “smurf mouth” methylene blue troches (use code BEN to save 10%). In this conversation, we dive into the science and potential of one of the most intriguing compounds in advanced wellness: cordycepin.

Dr. Scott Sherr is a Board-Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe), a specialist in Hyperbaric Oxygen Therapy (HBOT), and COO of Troscriptions. His clinical telepractice includes HOMe as its foundation alongside an integrative approach to HBOT that includes cutting-edge and dynamic HBOT protocols, comprehensive testing (using the HOMe framework), targeted supplementation, personal practices, synergistic technologies (new, ancient, psychedelic), and more.

Full show notes: https://bengreenfieldlife.com/sherr

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Sunlighten: Di

Mindsip insights from this episode:

Leverage AI to restore biological markers for optimal health

The future of medicine may involve AI that analyzes your health data to create plans aimed at restoring your biological markers to the optimal 21-to-30-year-old range.

#AI

#health

Dissolve trochies in upper cheek for optimal absorption

For better and faster absorption, dissolve trochies (medicated lozenges) in the upper cheek and gum area, which is more effective than swallowing or placing them under the tongue.

#supplement

Cycle cordycepin for optimal effectiveness

To maintain its effectiveness, it is best to cycle cordycepin by taking it for two to three weeks and then going off for a while, rather than using it continuously.

#supplement

Utilize cordycepin as a natural anti-viral supplement during travel

Cordycepin can act as an anti-infective by inhibiting RNA synthesis in viruses, making it a useful supplement to take when traveling or exposed to illness.

#antiviral

#supplement

Boost deep sleep with cordycepin in the evening

Taking cordycepin in the evening, as found in the product Troimmune, can significantly increase your deep sleep, an effect that is trackable on wearable devices.

#sleep

#supplement

Combine cordycepin with caffeine to boost energy

To counteract the sleepiness from cordycepin and direct its benefits toward energy production, you can take it with caffeine, which blocks the brain's adenosine receptors.

#biohacking

#energy

Utilize synthesized cordycepin for enhanced potency

The most active compound in the cordyceps mushroom is cordycepin, which only makes up about 0.03% of the mushroom by weight, so synthesized versions offer a much higher potency.

#mushroom

#supplement

Implement obligate pairing for effective GABA support

A new supplement strategy called 'obligate pairing' combines ingredients that stimulate GABA receptors with those that replete GABA itself to avoid tolerance and dependence.