Creatine supplementation may only offer noticeable brain improvements if your brain's creatine levels are low to begin with, similar to how extra fuel doesn't help a full gas tank.

A loading dose is not necessary and may cause stomach upset; taking 5 grams a day will saturate the muscles over a longer period with fewer side effects.

Contrary to old beliefs that it could cause gout, creatine appears to do the opposite by actually decreasing uric acid levels.

No study has ever shown that creatine accelerates hair loss, and the 2009 study that sparked this concern has never been replicated.

Researchers recently proposed creatine supplementation as a promising intervention for osteosarcopenia, the age-related decline in both bone and muscle health.

A recent study found that adding creatine to cognitive behavioral therapy significantly improved outcomes for patients with depression.

A meta-analysis revealed that creatine supplementation was particularly beneficial for females, challenging the idea that it is just a supplement for men.

Creatine supplementation can artificially raise blood creatinine levels, a marker for kidney function, making it appear that kidney health is worse than it actually is.