This Is Why Soda Spreads Cancer in your Body
Physionic
Nov 13, 2025
Episode description
JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 HEALTH AUTONOMY [COURSE]Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomyJOIN THE COMMUNITYJoin my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2EMAIL LIST1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6HIRE ME FOR CONSULTING: Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction0:40 - Soda and Cancer6:28 - Main Points / Key TakeawaysIncreased Cancer Risk Video linked at at the End: https://youtu.be/mZOCHKgsjCA?si=fSgkLkfilHj3skmRReferences[Study 541] Yun J, Feng T, Li Q, Liu Y, Jin Z, et al. Fructose metabolism promotes colorectal cancer metastasis through sorbitol dehydrogenase–dependent redox regulation. Nature Metabolism. 2025;7(10)Funding/Conflicts: Public Funding: National Institutes of Health (R01CA262437; R21CA258134; 5P01CA120964; 5P30CA006516); Cancer Prevention and Research Institute of Texas—CPRIT (RR170039; RP180734, also supporting Z.Z.); Non-Profit Funding: Pew-Stewart Scholar for Cancer Research Award; V Scholar Award; Andrew Sabin Family Fellows Award; Industry Funding: none reported; Conflicts of Interest: the authors declare no competing interests.[A] Hur J, Otegbeye E, Joh H-K, et al. Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women. Gut. Published online first: May 6, 2021. doi:10.1136/gutjnl-2020-323450. [B] Kanehara R, Park S-Y, Okada Y, Iwasaki M, Tsugane S, Sawada N, Inoue M, Haiman CA, Wilkens LR, Le Marchand L. Intake of sugar and food sources of sugar and colorectal cancer risk in the Multiethnic Cohort Study. J Nutr. 2024;154(5):2481–2492. doi:10.1016/j.tjnut.2024.05.016.CRITIQUES, RULES, AND NOTESBe aware of the following rules before posting comments:- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES:If your comment is rude, you will be banned.If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!). Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.
Mindsip insights from this episode:
Investigate SORD gene expression in cancerous tumors
Cancerous tumors have significantly higher expression of the SORD gene compared to normal, non-cancerous tissue.
Eliminate SORD to halt cancer metastasis
In animal studies, when the SORD enzyme was genetically removed from mice with cancer, metastasis (the spread of cancer) was massively diminished.
Understand soda's role in cancer spread through SORD enzyme
An enzyme called SORD is the newly discovered linchpin that explains how the combination of glucose and fructose in soda makes cancer spread more aggressively.
Inhibit SORD enzyme to disrupt fructose-fueled cancer growth
The SORD enzyme converts fructose to sorbitol, a process that increases NAD levels within the cell, which in turn activates the pro-invasion behavior of cancer cells.
Link sugar-sweetened beverages to increased cancer risk
Beyond animal models, several human studies also link sugar-sweetened beverages to higher cancer rates, even after controlling for diet quality and body weight.
Limit fructose and glucose to reduce colorectal cancer aggression
The combination of fructose plus glucose, common in soda, makes colorectal cancer cells significantly more aggressive and invasive compared to glucose alone.
Avoid soda and sugary drinks if diagnosed with colorectal cancer
A justified conclusion from the research is to avoid soda and other sugary drinks if you currently suffer from colorectal cancer.
