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0:00 - Introduction
0:21 - The Study
1:15 - The Coffee Molecule's Effects...
6:28 - Considerations
7:46 - Main Points

References
[Study 449] Wu C, Luan H, Zhang X, Wang S, Zhang X, Sun X, Guo P. Chlorogenic acid protects against atherosclerosis in ApoE−/− mice and promotes cholesterol efflux from RAW264.7 macrophages. PLoS One. 2014;9(9):e95452. doi:10.1371/journal.pone.0095452.

Funding/Conflicts: Public Funding [National Natural Sciences Foundation of China] / No direct Conflicts of Interest

[A] Naylor LH, Zimmermann D, Guitard-Uldry M, et al. Acute dose-response effect of coffee-derived chlorogenic acids on the human vasculature in healthy volunteers: a randomized controlled trial. Am J Clin Nutr. 2021;113(2):370-379. doi:10.1093/ajcn/nqaa312

[B] Lukitasari M, Saifur Rohman M, Nugroho DA, Widodo N, Nugrahini NIP. Cardiovascular protection effect of chlorogenic acid: focus on the molecular mechanism. F1000Res. 2020;9:1462. Published 2020 Dec 15. doi:10.12688/f1000research.26236.1

[C] Wang X, Ma H, Sun Q, et al. Coffee drinking timing and mortality in US adults. Eur Heart J. Published online January 8, 2025. doi:10.1093/eurheartj/ehae871

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