This Supplement mimics Anti-Arthritis Benefits of a Ketogenic Diet, without the Diet

Physionic

Jun 4, 2025

Episode description

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0:00 - Introduction
0:55 - Ketosis and Arthritis
2:21 - The Study
3:50 - Arthritis Relief?
5:00 - A Twist in the Story...
7:25 - I Disagree with the Researchers
9:21 - Main Points

Reference
[Study 458] Heidt C, Pons-Kühnemann J, Kämmerer U, Marquardt T, Reuss-Borst M. MCT-Induced Ketosis and Fiber in Rheumatoid Arthritis (MIKARA)-Study Protocol and Primary Endpoint Results of the Double-Blind Randomized Controlled Intervention Study Indicating Effects on Disease Activity in RA Patients. Nutrients. 2023;15(17):3719. Published 2023 Aug 25. doi:10.3390/nu15173719

Funding/Conflicts: Industry [Schär AG/SPA] // Potential direct Conflicts of Interest [One researcher is employed by the company]

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#rheumatoidarthritis #arthritisrelief

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
0:55 - Ketosis and Arthritis
2:21 - The Study
3:50 - Arthritis Relief?
5:00 - A Twist in the Story...
7:25 - I Disagree with the Researchers
9:21 - Main Points

Reference
[Study 458] Heidt C, Pons-Kühnemann J, Kämmerer U, Marquardt T, Reuss-Borst M. MCT-Induced Ketosis and Fiber in Rheumatoid Arthritis (MIKARA)-Study Protocol and Primary Endpoint Results of the Double-Blind Randomized Controlled Intervention Study Indicating Effects on Disease Activity in RA Patients. Nutrients. 2023;15(17):3719. Published 2023 Aug 25. doi:10.3390/nu15173719

Funding/Conflicts: Industry [Schär AG/SPA] // Potential direct Conflicts of Interest [One researcher is employed by the company]

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#rheumatoidarthritis #arthritisrelief

Mindsip insights from this episode:

Recognize researcher bias in MCT studies to ensure balanced insights

A potential conflict of interest, as the researchers work for a food company that sells MCTs, may have led to a reduced emphasis on the role of fiber.

Challenge conclusions on MCTs' impact based on data

The speaker argues that the researchers' conclusion that MCTs alone lead to improvements is not true according to their own data.

Combine MCTs and fiber to alleviate arthritis symptoms

The proper conclusion from the study is that the combination of Medium Chain Triglycerides (MCTs) plus fiber yields the beneficial effects on arthritis.

Supplementing with MCTs alone shows no improvement in rheumatoid arthritis symptoms

In a study on rheumatoid arthritis, supplementing with Medium Chain Triglycerides (MCTs) for the first eight weeks showed no statistically significant improvement in symptoms.

Utilize ketones to reduce inflammatory molecules in arthritis

Ketones may improve arthritis by reducing the production of specific inflammatory molecules like cytokines, interleukin 1 beta, interleukin 6, and interleukin 18.

Mimic ketogenic benefits for arthritis with supplements

You can potentially gain the arthritis-improving benefits of a ketogenic diet by using supplements to raise ketones, without having to adopt a very low carbohydrate diet.

Utilize MCTs and fiber to alleviate arthritis symptoms

The combination of MCTs and fiber led to a 5 to 6 point drop on the arthritis scale, enough to reclassify a person's symptoms to a more moderate level.

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