This Supplement mimics Anti-Arthritis Benefits of a Ketogenic Diet, without the Diet

Physionic

Jun 4, 2025

Episode description

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0:00 - Introduction
0:55 - Ketosis and Arthritis
2:21 - The Study
3:50 - Arthritis Relief?
5:00 - A Twist in the Story...
7:25 - I Disagree with the Researchers
9:21 - Main Points

Reference
[Study 458] Heidt C, Pons-Kühnemann J, Kämmerer U, Marquardt T, Reuss-Borst M. MCT-Induced Ketosis and Fiber in Rheumatoid Arthritis (MIKARA)-Study Protocol and Primary Endpoint Results of the Double-Blind Randomized Controlled Intervention Study Indicating Effects on Disease Activity in RA Patients. Nutrients. 2023;15(17):3719. Published 2023 Aug 25. doi:10.3390/nu15173719

Funding/Conflicts: Industry [Schär AG/SPA] // Potential direct Conflicts of Interest [One researcher is employed by the company]

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#rheumatoidarthritis #arthritisrelief

Mindsip insights from this episode:

Recognize researcher bias in MCT studies to ensure balanced insights

A potential conflict of interest, as the researchers work for a food company that sells MCTs, may have led to a reduced emphasis on the role of fiber.

#MCT

#research

Challenge conclusions on MCTs' impact based on data

The speaker argues that the researchers' conclusion that MCTs alone lead to improvements is not true according to their own data.

#MCT

#study

Combine MCTs and fiber to alleviate arthritis symptoms

The proper conclusion from the study is that the combination of Medium Chain Triglycerides (MCTs) plus fiber yields the beneficial effects on arthritis.

#fiber

#MCT

Supplementing with MCTs alone shows no improvement in rheumatoid arthritis symptoms

In a study on rheumatoid arthritis, supplementing with Medium Chain Triglycerides (MCTs) for the first eight weeks showed no statistically significant improvement in symptoms.

#arthritis

#MCT

Utilize ketones to reduce inflammatory molecules in arthritis

Ketones may improve arthritis by reducing the production of specific inflammatory molecules like cytokines, interleukin 1 beta, interleukin 6, and interleukin 18.

#arthritis

#inflammation

Mimic ketogenic benefits for arthritis with supplements

You can potentially gain the arthritis-improving benefits of a ketogenic diet by using supplements to raise ketones, without having to adopt a very low carbohydrate diet.

#arthritis

#supplement

Utilize MCTs and fiber to alleviate arthritis symptoms

The combination of MCTs and fiber led to a 5 to 6 point drop on the arthritis scale, enough to reclassify a person's symptoms to a more moderate level.