Nighttime erections are an important and measurable marker of cardiovascular and physiological health that decrease with age and poor sleep.

To achieve predictably perfect sleep, it is best to sleep alone to eliminate the variability in movement and schedules that a partner introduces.

Instead of letting your mind rule, you should treat your body as a democracy of organs, using data to create a protocol that takes better care of you than your own mind can.

The amount of deep and REM sleep you get is directly proportional to your willpower, making sleep the most critical intervention for improving self-control and health.

To stop self-sabotaging behaviors, personify the version of yourself that makes bad choices (e.g., "Evening Brian"), list their arguments, and formally fire them from making decisions.

You can gain roughly 32 years of life by not smoking, exercising six hours a week, maintaining a BMI between 18.5-22.5, eating a Blueprint-like diet, and consuming little to no alcohol.

For the first time in history, the rapid advancement of AI has created a 'wall of fog,' making it impossible for our intelligence to plan our lives more than three months into the future.

A new Follistatin gene therapy delivered via a plasmid is safer than previous versions because its effects can be turned off by taking an antibiotic like tetracycline.