I Read 250 Studies: 10 Things I Learned about your Health

Physionic

19 feb 2024

Episode description

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Created with Biorender
Videos on Studies:
GlyNAC (Full Analysis): https://youtu.be/6Lmc-mmqxyQ
Collagen (Full Analysis): https://youtu.be/pM5LdJkjy9Q
OMAD (Full Analysis): https://youtu.be/JKwC8sHEEjY
Reversing Aging/TRIIM Study: https://youtu.be/rVoxfABoHh4
Obese & Autophagy: https://youtu.be/F8arfpKri0M
Insulin vs Calories: https://youtu.be/wJh98sNrBzM
LDL on Heart Disease (Full Analysis): https://youtu.be/1t8rqfG1CMA
Urolithin A: https://youtu.be/cJdAlp2new4
Omega-3 on Cognition (Full Analysis): https://youtu.be/51sTitaUzJ8
Reversing Heart Disease (Full Analysis): https://youtu.be/obD1GBU8gik

0:00 - Something you should know...
0:48 - GlyNAC: Anti-Aging
3:09 - Collagen for Skin Aging
4:20 - OMAD for Health
6:34 - Reversing Aging
11:23 - Fatness increases Autophagy
14:50 - Calories or Insulin causing Fat Gain?
17:44 - LDL Particles on Heart Disease
21:32 - Urolithin A Supplementation
23:48 - Omega-3 for the Brain
26:12 - Reversing Atherosclerosis

********CRITIQUES, RULES, AND NOTES********

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Episode description

Mindsip insights from this episode:

Reverse atherosclerosis through lifestyle changes

Studies show that atherosclerosis (plaque buildup) can be reversed in humans through dedicated lifestyle changes like exercise, nutrition, and weight loss, not supplements.

#exercise

#heart

Use omega-3 supplements for cognitive improvement over time

Omega-3 supplements with a focus on DHA provide a small but consistent improvement in cognitive ability for those with mild impairment, but may require at least a year of use to see effects.

#cognition

#omega-3

Reassess Urolithin A supplements for limited benefits

A review of all human trials on Urolithin A supplementation found it had no statistically significant effect on mitochondrial production, and other health benefits were small or nonexistent.

#supplement

#urolithin

Recognize high LDL as a heart disease risk factor for all diets

Even for 'lean mass hyper-responders' on low-carb diets, current evidence does not prove that high LDL is benign, and it remains a primary heart disease risk factor.

#heart

#LDL

Recognize obesity's role in elevated autophagy markers

Contrary to the popular health narrative, tissue from obese individuals shows elevated markers of autophagy, which may be a response to inflammation rather than a sign of health.

#autophagy

#obesity

Reverse biological age with a rejuvenating cocktail

A study cocktail of HGH, DHEA, metformin, vitamin D, and zinc was shown to reverse biological age by years and restore the thymus gland from a fatty to a lean state.

#aging

#supplement

Avoid OMAD diet to maintain glucose tolerance

In studies where participants did not lose weight, a one-meal-a-day (OMAD) diet was shown to slightly worsen glucose tolerance.

#glucose

#nutrition

Leverage GlyNAC for health benefits in individuals over 60

The supplement GlyNAC (N-acetylcysteine and glycine) shows remarkable benefits for people in their 60s and beyond, but is unlikely to be beneficial for healthy individuals under 40 or 50.