#1 Exercise to Reverse Skin Aging

Physionic

Mar 12, 2025

Episode description

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*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

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Created with Biorender

0:00 - Introduction
0:35 - Study Background
1:00 - Skin Elasticity
1:43 - Skin Thickness
3:08 - Biglycan
5:09 - CCL28 Pro-Inflammation
6:43 - Main Points

References
[Study 418] Nishikori S, Yasuda J, Murata K, et al. Resistance training rejuvenates aging skin by reducing circulating inflammatory factors and enhancing dermal extracellular matrices. Sci Rep. 2023;13(1):10214. Published 2023 Jun 23. doi:10.1038/s41598-023-37207-9

Funding/Conflicts of Interest: Industry Funding [POLA Chemical Industries, Inc.] // Potential direct Conflicts of Interest [S. Nishikori, Y. Harada, and Y. Shirai are employees of POLA Chemical Industries, Inc.]

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#skincaretips #agingprevention #aginggracefully

Episode description

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*
Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2

*HEALTH AUTONOMY [COURSE]*
Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy

*JOIN THE COMMUNITY*
Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2

*EMAIL LIST*
1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6

*HIRE ME FOR CONSULTING:*
Consulting: https://bit.ly/3dmUl2H

Created with Biorender

0:00 - Introduction
0:35 - Study Background
1:00 - Skin Elasticity
1:43 - Skin Thickness
3:08 - Biglycan
5:09 - CCL28 Pro-Inflammation
6:43 - Main Points

References
[Study 418] Nishikori S, Yasuda J, Murata K, et al. Resistance training rejuvenates aging skin by reducing circulating inflammatory factors and enhancing dermal extracellular matrices. Sci Rep. 2023;13(1):10214. Published 2023 Jun 23. doi:10.1038/s41598-023-37207-9

Funding/Conflicts of Interest: Industry Funding [POLA Chemical Industries, Inc.] // Potential direct Conflicts of Interest [S. Nishikori, Y. Harada, and Y. Shirai are employees of POLA Chemical Industries, Inc.]

********CRITIQUES, RULES, AND NOTES********

Be aware of the following rules before posting comments:
- Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce).

Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:

Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached.

RULES:
If your comment is rude, you will be banned.
If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response.

If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!).

Please use the following link to submit your critique: https://bit.ly/PhysionicCritique

Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

#skincaretips #agingprevention #aginggracefully

Mindsip insights from this episode:

Train twice a week for skin improvement benefits

The study participants who experienced skin improvements from resistance training only exercised twice a week, suggesting high frequency may not be necessary.

Prioritize resistance training for youthful skin thickness

In a study comparing exercise types, resistance training was shown to be superior to aerobic training for improving dermal thickness, a key marker of youthful skin.

Boost resistance training to enhance Biglycan for skin structure

Resistance training uniquely increases the gene for Biglycan, an essential protein that anchors and organizes collagen fibers to give skin its structure.

Lift weights to reduce skin inflammation and enhance skin health

Resistance training appears to improve skin by lowering levels of an inflammatory molecule, CCL28, which is correlated with higher levels of the skin-structuring protein Biglycan.

Combat chronic inflammation to protect skin health

Cell experiments indicate that the inflammatory molecule CCL28 directly suppresses Biglycan, providing a mechanism for how chronic inflammation can degrade skin health.

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