
#1 LONGEVITY SCIENTIST Reveals The Optimal Diet & Fasting Window For Longevity | Valter Longo, Ph.D
Rich Roll
Feb 10, 2025
Mindsip insights from this episode:
Prioritize amino acid profiles over protein sources
The term 'protein' is almost irrelevant because the specific amino acid profile is what matters, which can differ by up to ten-fold between various sources.
Implement 12-hour eating window for effective time-restricted eating
A 12-hour eating and 12-hour fasting window is the safest, easiest, and most effective approach to daily time-restricted eating for the general population.
Incorporate Fasting Mimicking Diet to enhance cancer survival rates
In a study on women with metastatic triple-negative breast cancer, adding the Fasting Mimicking Diet to chemotherapy nearly doubled their overall survival.
Avoid extreme biohacking to prevent long-term health risks
Taking hundreds of supplements and following extreme eating windows is a huge gamble, as the complex interactions and unknown long-term effects could lead to a big, negative surprise 25 years later.
Adjust protein intake after age 65 for optimal health
Data suggests a low-protein diet is best for longevity up to age 65, after which a higher protein intake becomes more beneficial for health.
Utilize Fasting Mimicking Diet to preserve and increase lean body mass
Unlike GLP-1 agonists, multiple trials show that the Fasting Mimicking Diet does not cause lean body mass loss and can even increase it when combined with a healthy diet.
Avoid refeeding during chemotherapy to protect heart health
Refeeding while chemotherapy drugs are still high in your system is a very bad combination that can increase toxicity to the heart.
Implement periodic fasting to avoid 'thrifty mode' and enhance fat burning
Prolonged restriction can trigger a long-lasting, energy-saving 'thrifty mode,' making weight loss impossible, which is why periodic fasting is designed to switch to fat-burning without this negative effect.
Trigger cellular reprogramming through fasting
Fasting activates the body's innate ability to fix itself by turning on regenerative programs that reprogram cells, similar to how organs are first generated.
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