America’s Obesity Crisis: Is Ozempic a Cure or a Cover-Up? | Calley Means and Tyna Moore

Mark Hyman

Feb 17, 2025

Episode description

The rise in obesity and chronic disease over the years is alarming. Rather than genetics, it can be attributed to environmental and dietary changes, emphasizing the role of food quality over quantity. And while GLP-1 agonists like Ozempic may show some promise in addressing metabolic dysfunction, concerns about long-term effects, muscle loss, and cost highlight the need for a more nuanced approach. Ultimately, a holistic strategy that includes diet, lifestyle, and personalized interventions is essential for sustainable health improvements.

In this episode I discuss, along with Dr. Tyna Moore and Calley Means, the complexity of obesity, moving beyond the simplistic "calories in, calories out" model to focus on factors like insulin resistance, ultra-processed foods, and metabolic dysfunction.

With nearly three decades experience in the medical world, Dr Tyna Moore is a leading expert in holistic regenerative medicine and resilient, metabolic health. Traditionally and alternatively trained in science and medicine as both a Naturopathic Physician and Chiropractor, she brings a unique perspective to those wishing to build a more robust foundation in their health and well-being. She is a podcast host, author, speaker, kettlebell devotee and mother. She is a fierce advocate for health autonomy and personal responsibility, which she helps others improve through her many offerings at drtyna.com and on her podcast, The Dr Tyna Show. Her true passion is coaching healthcare practitioners to utilize social media and build the online business of their dreams so they aren’t shackled by illegal mandates and can enjoy more time, money and autonomy.

Calley Means is the founder of TrueMed, a company that enables tax-free spending on food and exercise. He is also the co-author with his sister, Dr. Casey Means, ofGood Energy: The Surprising Connection Between Metabolism and Limitless Health, and is now available for pre-order.Earlier in his career, Calley was a consultant for food and pharma companies and is now exposing practices they use to weaponize our institutions of trust. In the past year, he’s met with 50 members of Congress and presidential candidates advocating policies to combat the corruption of the pharma and food industries. He is a graduate of Stanford and Harvard Business School.

Full length episodes can be found here:

Can Ozempic Fix Our Obesity Crisis

Ozempic: A Weight-Loss Miracle of Metabolic Menace?

The Science of Weight Loss: What You Need to Know

This episode is brought to you by BIOptimizers.

Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Episode description

The rise in obesity and chronic disease over the years is alarming. Rather than genetics, it can be attributed to environmental and dietary changes, emphasizing the role of food quality over quantity. And while GLP-1 agonists like Ozempic may show some promise in addressing metabolic dysfunction, concerns about long-term effects, muscle loss, and cost highlight the need for a more nuanced approach. Ultimately, a holistic strategy that includes diet, lifestyle, and personalized interventions is essential for sustainable health improvements.

In this episode I discuss, along with Dr. Tyna Moore and Calley Means, the complexity of obesity, moving beyond the simplistic "calories in, calories out" model to focus on factors like insulin resistance, ultra-processed foods, and metabolic dysfunction.

With nearly three decades experience in the medical world, Dr Tyna Moore is a leading expert in holistic regenerative medicine and resilient, metabolic health. Traditionally and alternatively trained in science and medicine as both a Naturopathic Physician and Chiropractor, she brings a unique perspective to those wishing to build a more robust foundation in their health and well-being. She is a podcast host, author, speaker, kettlebell devotee and mother. She is a fierce advocate for health autonomy and personal responsibility, which she helps others improve through her many offerings at drtyna.com and on her podcast, The Dr Tyna Show. Her true passion is coaching healthcare practitioners to utilize social media and build the online business of their dreams so they aren’t shackled by illegal mandates and can enjoy more time, money and autonomy.

Calley Means is the founder of TrueMed, a company that enables tax-free spending on food and exercise. He is also the co-author with his sister, Dr. Casey Means, ofGood Energy: The Surprising Connection Between Metabolism and Limitless Health, and is now available for pre-order.Earlier in his career, Calley was a consultant for food and pharma companies and is now exposing practices they use to weaponize our institutions of trust. In the past year, he’s met with 50 members of Congress and presidential candidates advocating policies to combat the corruption of the pharma and food industries. He is a graduate of Stanford and Harvard Business School.

Full length episodes can be found here:

Can Ozempic Fix Our Obesity Crisis

Ozempic: A Weight-Loss Miracle of Metabolic Menace?

The Science of Weight Loss: What You Need to Know

This episode is brought to you by BIOptimizers.

Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Mindsip insights from this episode:

Beware Ozempic's severe side effect risks

In one study, Ozempic-like drugs increased the risk of stomach paralysis by 367%, pancreatitis by 900%, and bowel obstruction by 422%.

Beware muscle loss with Ozempic use

When using drugs like Ozempic, 40% of the weight lost is muscle, which is the key to your metabolism.

Learn from Pottinger's cats: avoid processed diets for health

A 1930s study on cats showed that a processed diet led to infertility and disease within three generations, mirroring our current human health crisis.

Microdose GLP-1s to gain benefits without side effects

Using GLP-1 agonists at a microdose, such as a fifth of the standard starting dose, may provide benefits for conditions like autoimmune disease and high blood pressure without the severe side effects.

Address GLP-1 deficiency to combat obesity and metabolic dysfunction

Obesity and metabolic dysfunction may be linked to a deficiency in the GLP-1 hormone, potentially caused by genetic mutations or our toxic food environment.

Investigate GLP-1 agonists for neuroinflammation and joint health

Contrary to popular belief, GLP-1 agonists are being studied for their positive, regenerative impacts on neuroinflammation, Alzheimer's, Parkinson's, and joint cartilage.

Recognize whole foods provide fewer calories than labeled

The body extracts significantly fewer calories from whole foods like nuts than what is listed on the label, with almonds providing 32% less energy than stated.

Understand carbohydrate-insulin model to combat obesity

The carbohydrate-insulin model posits that refined carbs and sugar drive high levels of insulin, the fat-storage hormone that locks fat in cells and slows metabolism.

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