Are YOU Taking Too Many Supplements, Doing Too Much Ice Bathing Or Eating the Wrong Diet? (Here's How To Know!) With MeScreen's Sean Fetcho & Dr. Luis Fandos
Ben Greenfield
Nov 13, 2025
Mindsip insights from this episode:
Incorporate CoQ10, alpha-lipoic acid, and acetyl-L-carnitine for mitochondrial support
Based on test data, common supplements recommended for improving mitochondrial function include CoQ10, alpha-lipoic acid, and acetyl-L-carnitine.
Utilize finger-prick test to replace painful muscle biopsies
This new finger-prick test provides the same data as the previous gold standard, which was a painful and expensive 6-inch needle muscle tissue biopsy.
Prioritize weight training for optimal mitochondrial health
Weight training is considered more important for mitochondrial health than excessive running, which can raise cortisol and reduce mitochondrial efficiency.
Leverage mitochondrial network for optimal energy allocation
Mitochondria form a network and communicate chemically throughout the body to allocate energy resources where they are needed most, such as to the brain during a test.
Monitor mitochondrial function over 90 days for stable health insights
Unlike daily fluctuating biomarkers, your mitochondrial function takes over 90 days to show significant physiological change, making it a stable long-term health metric.
Limit cold plunging to maintain mitochondrial efficiency and reduce inflammation
Excessive cold plunging can cause too much mitochondrial uncoupling, which reduces energy (ATP) efficiency and creates inflammatory stress.
Transform inherited mitochondrial destiny through lifestyle choices
Even though you inherit mitochondrial DNA from your mother, you can change the behavior of those genes through epigenetics like diet, sleep, and exercise.
Identify your mitochondrial health profile from 17 distinct categories
Every single person on the planet falls into one of 17 distinct profiles of mitochondrial health, which are classified based on your test score.
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