
Does Canola Oil cause Inflammation? Every RCT Analyzed. [Study 401-410 Analysis]
Physionic
Jun 28, 2025
Mindsip insights from this episode:
Clarify subclinical inflammation as oxidative stress damage
The term 'subclinical inflammation' is often used without a clear definition, but can be interpreted as cellular damage from oxidative stress, such as lipid peroxidation.
Pair fried foods with antioxidants to reduce inflammation
Consuming fried foods as part of a meal rich in antioxidants, such as lots of greens, may help counteract the potential inflammatory effects from the repeatedly heated oil.
Incorporate cold canola oil for potential anti-inflammatory benefits
Based on a comprehensive review of human intervention trials, consuming cold canola oil appears to be either neutral or beneficial for your inflammatory state.
Critique flawed heated oil study for accurate conclusions
The study on heated oil used a blend of 70% canola and 30% sunflower oil, making it difficult to isolate and blame canola oil alone for the negative results.
Understand limitations of heated oil study for home cooking
The only study showing negative effects used oil heated 20 times to 180°C (356°F), an extreme scenario more applicable to commercial deep fryers than typical home cooking.
Question dimethyl polysiloxane's antioxidant role in frying oils
A chemical called dimethyl polysiloxane is often added to commercial frying oils to reduce foaming, and while it has real-world applicability, its role as an antioxidant is questionable.
Critique short-term studies for meaningful health insights
The speaker criticizes one study as 'laughable' for attempting to measure artery plaque changes over just four weeks, a timeframe too short for meaningful results.
Utilize canola oil to reduce inflammation like olive oil
In a study on overweight women with type 2 diabetes, both canola and olive oil significantly reduced the key inflammatory marker C-reactive protein (CRP).
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